Wednesday, March 15, 2017
Genome editing Why the CRISPR patent verdict isn’t the end of the story Burstein D, Harrington LB, Strutt SC, Probst AJ, Anantharaman K, Thomas BC, Doudna JA, Banfield JF. New CRISPR-Cas systems from uncultivated microbes. Nature. 2017 Feb 9;542(7640):237-241. doi: 10.1038/nature21059. PubMed PMID: 28005056; PubMed Central PMCID: PMC5300952. Imaging Pan C, Cai R, Quacquarelli FP, […]
Genome Editing Bolukbasi MF, Gupta A, Oikemus S, Derr AG, Garber M, Brodsky MH, Zhu LJ, Wolfe SA. DNA-binding-domain fusions enhance the targeting range and precision of Cas9. Nat Methods. 2015 Oct 19. doi: 10.1038/nmeth.3624. [Epub ahead of print] PubMed PMID: 26480473. Thakore PI, D’Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy […]
Tuesday, December 1, 2015
Imaging Ariotti N, Hall TE, Rae J, Ferguson C, McMahon KA, Martel N, Webb RE, Webb RI, Teasdale RD, Parton RG. Modular Detection of GFP-Labeled Proteins for Rapid Screening by Electron Microscopy in Cells and Organisms. Dev Cell. 2015 Nov 11. pii: S1534-5807(15)00681-4. doi: 10.1016/j.devcel.2015.10.016. [Epub ahead of print] PubMed PMID: 26585296. Genomics Bhaduri A, […]
Population Genetics Balaresque P, Poulet N, Cussat-Blanc S, Gerard P, Quintana-Murci L, Heyer E, Jobling MA. Y-chromosome descent clusters and male differential reproductive success: young lineage expansions dominate Asian pastoral nomadic populations. Eur J Hum Genet. 2015 Jan 14. doi: 10.1038/ejhg.2014.285. [Epub ahead of print] PubMed PMID: 25585703. Nature News: Genghis Khan’s genetic legacy has […]
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Also tagged 3d printing, development, evolution, funding, genetics, Genome editing, genomics, imaging, neuroscience, population genetics, prosthetics, research career, retinal development
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Saturday, January 10, 2015
Retinal development Masuda T, Zhang X, Berlinicke C, Wan J, Yerrabelli A, Conner EA, Kjellstrom S, Bush R, Thorgeirsson SS, Swaroop A, Chen S, Zack DJ. The Transcription Factor GTF2IRD1 Regulates the Topology and Function of Photoreceptors by Modulating Photoreceptor Gene Expression across the Retina. J Neurosci. 2014 Nov 12;34(46):15356-68. Okabe K, Kobayashi S, Yamada […]
Genome Editing Gagnon JA, Valen E, Thyme SB, Huang P, Ahkmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs. PLoS One. 2014 May 29;9(5):e98186. doi: 10.1371/journal.pone.0098186. eCollection 2014. PubMed PMID: 24873830. Hsu PD, Lander ES, Zhang F. Development and […]
Gene regulatory network Barsi JC, Tu Q, Davidson E. General approach for in vivo recovery of cell type specific effector gene sets. Genome Res. 2014 Mar 6. [Epub ahead of print] PubMed PMID: 24604781. Medicine Project to Improve Poor Children’s Intellect Led to Better Health, Data Show Begley CG, Ellis LM. Drug development: Raise standards […]
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Also tagged CRISPR, CRISPR-CAS, development, gene regulatory network, genetics, Genome editing, neuroscience, regenerative medicine, retina, retinal degeneration, retinal development, retinal regeneration, stem cells, synthetic biology, TALEN
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Genomics Venter’s New Goal: World’s Largest Sequencing Operation Clinical Whole Genome Sequencing: Not Quite Ready for Prime Time? Genetics Vanderperre B, Lucier JF, Bissonnette C, Motard J, Tremblay G, Vanderperre S, Wisztorski M, Salzet M, Boisvert FM, Roucou X. Direct detection of alternative open reading frames translation products in human significantly expands the proteome. PLoS […]
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Also tagged academic career, AIDS, alternative open reading frames, Alzheimer's Disease, diabetes, evolution, eye disease, genetics, Genome editing, genomics, HIV, imaging, neuroscience, olfactory, paper microscope, Philosophy, resistance, retinitis pigmentosa, scientific publishing, sequencing, smell, STAP, stem cells, vision, zebrafish, zinc finger nucleases
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This is a collection of the videos that I used in lab discussion section of the ethical issues in human embryonic stem cells research in the 2014 BIOL36701 Principles Development at Purdue University. 1. An introduction to stem cell – A stem cell story 2. Are embryos persons? 3. A question of balance? 4. How […]
Saturday, December 28, 2013
Neuroscience Widmann A, Schröger E. Filter effects and filter artifacts in the analysis of electrophysiological data. Front Psychol. 2012 Jul 9;3:233. doi: 10.3389/fpsyg.2012.00233. eCollection 2012. PubMed PMID: 22787453; PubMed Central PMCID: PMC3391960. Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK. Microbiota modulate behavioral […]
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Also tagged biochemistry, Connectomics, CRISPR, CRISPR-CAS, development, electrophysiology, evolution, funding, gene regulatory network, genetics, Genome editing, genomics, imaging, Microscopy, neuroscience, retina, RNA-seq, stem cells, super-resolution imaging, systems biology, TALEN, zebrafish
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