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2015-12-07 New articles we read this week

Genome Editing

  1. Bolukbasi MF, Gupta A, Oikemus S, Derr AG, Garber M, Brodsky MH, Zhu LJ, Wolfe SA. DNA-binding-domain fusions enhance the targeting range and precision of Cas9. Nat Methods. 2015 Oct 19. doi: 10.1038/nmeth.3624. [Epub ahead of print] PubMed PMID: 26480473.
  2. Thakore PI, D’Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy TE, Crawford GE, Gersbach CA. Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements. Nat Methods. 2015 Oct 26. doi: 10.1038/nmeth.3630. [Epub ahead of print] PubMed PMID: 26501517.
  3. Nature Outlook: Genome Editing

Science Career

  1. Ma A, Mondragón RJ, Latora V. Anatomy of funded research in science. Proc Natl Acad Sci U S A. 2015 Oct 26. pii: 201513651. [Epub ahead of print] PubMed PMID: 26504240.
  2. Gould J. How to build a better PhD. Nature. 2015 Dec 2;528(7580):22-5. doi: 10.1038/528022a. PubMed PMID: 26632571.
  3. Make the most of PhDs. Nature. 2015 Dec 2;528(7580):7. doi: 10.1038/528007a. PubMed PMID: 26632550.


  1. Nikolaou N, Meyer MP. Lamination Speeds the Functional Development of Visual Circuits. Neuron. 2015 Nov 18. pii: S0896-6273(15)00886-7. doi: 10.1016/j.neuron.2015.10.020. [Epub ahead of print] PubMed PMID: 26607001.


  1. Pankow S, Bamberger C, Calzolari D, Martínez-Bartolomé S, Lavallée-Adam M, Balch WE, Yates JR 3rd. ∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis. Nature. 2015 Nov 30. doi: 10.1038/nature15729. [Epub ahead of print] PubMed PMID: 26618866.


  1. Li IJ, Chang CJ, Liu SC, Abe G, Ota KG. Postembryonic staging of wild-type goldfish, with brief reference to skeletal systems. Dev Dyn. 2015 Aug 28. doi: 10.1002/dvdy.24340. [Epub ahead of print] PubMed PMID: 26316229.

Systems Biology

  1. Keren L, van Dijk D, Weingarten-Gabbay S, Davidi D, Jona G, Weinberger A, Milo R, Segal E. Noise in gene expression is coupled to growth rate. Genome Res. 2015 Dec;25(12):1893-902. doi: 10.1101/gr.191635.115. Epub 2015 Sep 9. PubMed PMID: 26355006.