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Tag Archives: medicine

2013-10-12 New articles we read this week

Saturday, October 12, 2013

Genetics/Genomics Mali P, Esvelt KM, Church GM. Cas9 as a versatile tool for engineering biology. Nat Methods. 2013 Sep 27;10(10):957-63. doi: 10.1038/nmeth.2649. PubMed  PMID: 24076990. Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM. Orthogonal Cas9 proteins for RNA-guided gene regulation and editing. Nat Methods. 2013 Sep 29. doi: 10.1038/nmeth.2681. [Epub ahead of print] PubMed […]

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2013-09-29 new articles we read this week

Sunday, September 29, 2013

Stem cells Abad M, Mosteiro L, Pantoja C, Cañamero M, Rayon T, Ors I, Graña O, Megías D, Domínguez O, Martínez D, Manzanares M, Ortega S, Serrano M. Reprogramming in vivo produces teratomas and iPS cells with totipotency features. Nature. 2013 Sep 11. doi: 10.1038/nature12586. [Epub ahead of print] PubMed PMID: 24025773. Commentary: De Los Angeles […]

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2012-10-28 new articles we read this week

Sunday, October 28, 2012

Science special section – Forces in Development Purnell BA. Forces in development. Forceful thinking. Introduction. Science. 2012 Oct 12;338(6104):209. doi: 10.1126/science.338.6104.209. PubMed PMID: 23066070. Kicheva A, Cohen M, Briscoe J. Developmental pattern formation: insights from physics and biology. Science. 2012 Oct 12;338(6104):210-2. doi: 10.1126/science.1225182. Review. PubMed PMID: 23066071. Furusawa C, Kaneko K. A dynamical-systems view […]

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The Nobel Prize in Physiology or Medicine 2012

Monday, October 8, 2012

was awarded jointly to Sir John Gurdon and Shinya Yamnaka “for the discovery that mature cells can be reprogrammed to become pluripotent” They also won the Lasker Award in 2009.  

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2012-09-10 New articles we read this week

Tuesday, September 11, 2012

Retinal Development Salbreux G, Barthel LK, Raymond PA, Lubensky DK. Coupling mechanical deformations and planar cell polarity to create regular patterns in the zebrafish retina. PLoS Comput Biol. 2012 Aug;8(8):e1002618. Epub 2012 Aug 23. PubMed PMID: 22936893; PubMed Central PMCID: PMC3426565. Chen M, Wang K, Lin B. Development and degeneration of cone bipolar cells are  […]

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2012-05-16 New articles we read this week

Wednesday, May 16, 2012

Neuroimaging/ Connectomics Wedeen VJ, Rosene DL, Wang R, Dai G, Mortazavi F, Hagmann P, Kaas JH, Tseng WY. The geometric structure of the brain fiber pathways. Science. 2012 Mar 30;335(6076):1628-34. PubMed PMID: 22461612. Neuroscience Rogulja D, Young MW. Control of sleep by cyclin A and its regulator. Science. 2012 Mar 30;335(6076):1617-21. PubMed PMID: 22461610. Koch […]

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How Doctors (Physicians) Die

Thursday, December 29, 2011

How Doctors Die – It’s Not Like the Rest of Us, But It Should Be A deep article written by Ken Murray about how some physicians and patients would opt for less or no treatments when they encounter terminal illness.

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2011-12-03 New articles we read this week

Saturday, December 3, 2011

Medicine There seems to be a new effective drug for Cystic Fibrosis! Ramsey BW, Davies J, McElvaney NG, Tullis E, Bell SC, Dřevínek P, Griese M, McKone EF, Wainwright CE, Konstan MW, Moss R, Ratjen F, Sermet-Gaudelus I, Rowe SM, Dong Q, Rodriguez S, Yen K, Ordoñez C, Elborn JS; VX08-770-102 Study Group. A CFTR […]

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The Mouse Trap – the issues with using animal model for medical research

Thursday, November 17, 2011

I just come across with this article in Slate Magazine “The Mouse Trap – The dangers of using one lab animal to study every disease.” that talks in great details about the limitation of using animal model to look for new drugs to treat human diseases.  For example, the control healthy mouse can actually be […]

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The genome of the naked mole rat!

Thursday, November 3, 2011

The genome sequence of the naked mole rat is published recently (Kim et al., 2011) ! This is an amazing creature that lives almost up to 30 years in captivity, 9 times longer than mice. At the same time they do not seem to suffer from cancer or a decline in fertility (Buffenstein 2008). I […]

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