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Tag Archives: gene regulatory network

Uri Alon: Why truly innovative science demands a leap into the unknown

Sunday, June 22, 2014

Just saw this from a friend’s share. It is a great TED talk by Uri Alon on his experience on doing innovative science.   His work has inspired many including myself. Here are a few seminal papers by his groups. Milo R, Shen-Orr S, Itzkovitz S, Kashtan N, Chklovskii D, Alon U. Network motifs: simple […]

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2014-06-21 new articles we read this week

Saturday, June 21, 2014

Stem cells/ regenerative medicine Zhong X, Gutierrez C, Xue T, Hampton C, Vergara MN, Cao LH, Peters A, Park TS, Zambidis ET, Meyer JS, Gamm DM, Yau KW, Canto-Soler MV. Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat Commun. 2014 Jun 10;5:4047. doi: 10.1038/ncomms5047. PubMed PMID: 24915161. Reichman S, Terray A, […]

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2014-06-07 New articles we read this week

Saturday, June 7, 2014

Genome Editing Gagnon JA, Valen E, Thyme SB, Huang P, Ahkmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs. PLoS One. 2014 May 29;9(5):e98186. doi: 10.1371/journal.pone.0098186. eCollection 2014. PubMed PMID: 24873830. Hsu PD, Lander ES, Zhang F. Development and […]

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2014-05-25 new articles we read this week

Sunday, May 25, 2014

Gene regulatory network Barsi JC, Tu Q, Davidson E. General approach for in vivo recovery of cell type specific effector gene sets. Genome Res. 2014 Mar 6. [Epub ahead of print] PubMed PMID: 24604781. Medicine Project to Improve Poor Children’s Intellect Led to Better Health, Data Show Begley CG, Ellis LM. Drug development: Raise standards […]

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2013-12-28 New articles we read this week

Saturday, December 28, 2013

Neuroscience Widmann A, Schröger E. Filter effects and filter artifacts in the analysis of  electrophysiological data. Front Psychol. 2012 Jul 9;3:233. doi: 10.3389/fpsyg.2012.00233. eCollection 2012. PubMed PMID: 22787453; PubMed Central PMCID: PMC3391960. Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK. Microbiota modulate behavioral […]

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2012-02-05 new articles we read this week

Sunday, February 5, 2012

Development Balaskas N, Ribeiro A, Panovska J, Dessaud E, Sasai N, Page KM, Briscoe J, Ribes V. Gene regulatory logic for reading the sonic hedgehog signaling gradient in the vertebrate neural tube. Cell. 2012 Jan 20;148(1-2):273-84. PubMed PMID: 22265416; PubMed Central PMCID: PMC3267043. Lassar A. Finding MyoD with a little help from my friends. Nat […]

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The differentiation circuit of dopamine-secreting neurons

Tuesday, June 2, 2009

There are so many different kinds of neurons in the brain and they control all sorts of mechanisms. In C.elegans, several dopamine(a neurotransmitter) -secreting neurons are differentiated from different lineage, but they are all producing dopamine. This has raised an interesting question: are the genes controlling the dopamine synthesis regulated differently or the same way […]

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