Saturday, December 28, 2013
Neuroscience Widmann A, Schröger E. Filter effects and filter artifacts in the analysis of electrophysiological data. Front Psychol. 2012 Jul 9;3:233. doi: 10.3389/fpsyg.2012.00233. eCollection 2012. PubMed PMID: 22787453; PubMed Central PMCID: PMC3391960. Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK. Microbiota modulate behavioral […]
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Also tagged biochemistry, Connectomics, CRISPR, CRISPR-CAS, development, electrophysiology, funding, gene regulatory network, genetics, Genome editing, genomics, imaging, medicine, Microscopy, neuroscience, retina, RNA-seq, stem cells, super-resolution imaging, systems biology, TALEN, zebrafish
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Genomics Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013 Oct 21;14(10):R115. [Epub ahead of print] PubMed PMID: 24138928. News coverage: Scientists Discover New Biological Clock With Age-Measuring Potential News: FDA Tells Google-Backed 23andMe to Halt DNA Test Service Evolution Kolb AW, Ané C, Brandt CR. Using HSV-1 Genome Phylogenetics to Track Past Human […]
Evolution Feuda R, Hamilton SC, McInerney JO, Pisani D. Metazoan opsin evolution reveals a simple route to animal vision. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):18868-72. doi: 10.1073/pnas.1204609109. Epub 2012 Oct 29. PubMed PMID: 23112152; PubMed Central PMCID: PMC3503164. News article: Vision evolved 700 million years ago Genetics Cong L, Ran FA, […]
Evolution Ramani AK, Chuluunbaatar T, Verster AJ, Na H, Vu V, Pelte N, Wannissorn N, Jiao A, Fraser AG. The majority of animal genes are required for wild-type fitness. Cell. 2012 Feb 17;148(4):792-802. PubMed PMID: 22341449. Loehlin DW, Werren JH. Evolution of shape by multiple regulatory changes to a growth gene. Science. 2012 Feb 24;335(6071):943-7. […]
Saturday, January 14, 2012
Retinal Development Kwan KM, Otsuna H, Kidokoro H, Carney KR, Saijoh Y, Chien CB. A complex choreography of cell movements shapes the vertebrate eye. Development. 2012 Jan;139(2):359-72. PubMed PMID: 22186726. Morgan JL, Soto F, Wong RO, Kerschensteiner D. Development of cell type-specific connectivity patterns of converging excitatory axons in the retina. Neuron. 2011 Sep 22;71(6):1014-21. […]
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Also tagged education, genetics, genomics, medical research, neuroscience, retinal development, stem cells, systems biology, vision, zebrafish
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Sunday, November 20, 2011
Medical Research *These two articles point out the problems of using animal models for research if the goal is to extract translational values and how mouse model, the gold standard for disease research, can actually be a poor reference standard because of the ways we want to standardize the biological tool for testing. Lynch VJ. […]
I read several classic papers when I am planning projects with some of you. This is a very good review paper on the fundamental architecture of retina. There are a lot useful histological facts and observations. It has great discussions on how the retinal architecture has evolved and in turn provides the necessary visual functions […]
This is a series of papers from a recent Sackler colloquium of the National Academy of Sciences entitled “In the Light of Evolution III: Two Centuries of Darwin“. You can watch most of the presentations online here. The conference papers are published in a supplemental issue of the PNAS. I read Daniel Dennett‘s paper because […]
Why do we laugh? Is there any evolutionary significance? Well, instead of pondering about these questions… why not tickle a primate to find it out? Humans aren’t the only ones who like it in the armpit. Our fellow great apes — orangutans, chimps, bonobos and gorillas — also squeal in response to tickling, and new […]
A fundamental but elusive step in the early evolution of life on Earth has been replicated in a laboratory. Researchers synthesized the basic ingredients of RNA, a molecule from which the simplest self-replicating structures are made. Until now, they couldn’t explain how these ingredients might have formed. …. No matter how they combined the ingredients […]