Development Eom DS, Bain EJ, Patterson LB, Grout ME, Parichy DM. Long-distance communication by specialized cellular projections during pigment pattern development and evolution. Elife. 2015 Dec 23;4. pii: e12401. doi: 10.7554/eLife.12401. [Epub ahead of print] PubMed PMID: 26701906. Stem cells Shirai H, Mandai M, Matsushita K, Kuwahara A, Yonemura S, Nakano T, Assawachananont J, Kimura […]
Genome Editing Bolukbasi MF, Gupta A, Oikemus S, Derr AG, Garber M, Brodsky MH, Zhu LJ, Wolfe SA. DNA-binding-domain fusions enhance the targeting range and precision of Cas9. Nat Methods. 2015 Oct 19. doi: 10.1038/nmeth.3624. [Epub ahead of print] PubMed PMID: 26480473. Thakore PI, D’Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy […]
Imaging Ariotti N, Hall TE, Rae J, Ferguson C, McMahon KA, Martel N, Webb RE, Webb RI, Teasdale RD, Parton RG. Modular Detection of GFP-Labeled Proteins for Rapid Screening by Electron Microscopy in Cells and Organisms. Dev Cell. 2015 Nov 11. pii: S1534-5807(15)00681-4. doi: 10.1016/j.devcel.2015.10.016. [Epub ahead of print] PubMed PMID: 26585296. Genomics Bhaduri A, […]
Population Genetics Balaresque P, Poulet N, Cussat-Blanc S, Gerard P, Quintana-Murci L, Heyer E, Jobling MA. Y-chromosome descent clusters and male differential reproductive success: young lineage expansions dominate Asian pastoral nomadic populations. Eur J Hum Genet. 2015 Jan 14. doi: 10.1038/ejhg.2014.285. [Epub ahead of print] PubMed PMID: 25585703. Nature News: Genghis Khan’s genetic legacy has […]
Cell cycle Malumbres M. Cyclin-dependent kinases. Genome Biol. 2014;15(6):122. PubMed PMID: 25180339; PubMed Central PMCID: PMC4097832. Sequencing/Disease Gilissen C, Hehir-Kwa JY, Thung DT, van de Vorst M, van Bon BW, Willemsen MH, Kwint M, Janssen IM, Hoischen A, Schenck A, Leach R, Klein R, Tearle R, Bo T, Pfundt R, Yntema HG, de Vries BB, […]
Gene regulatory network Barsi JC, Tu Q, Davidson E. General approach for in vivo recovery of cell type specific effector gene sets. Genome Res. 2014 Mar 6. [Epub ahead of print] PubMed PMID: 24604781. Medicine Project to Improve Poor Children’s Intellect Led to Better Health, Data Show Begley CG, Ellis LM. Drug development: Raise standards […]
Genomics Venter’s New Goal: World’s Largest Sequencing Operation Clinical Whole Genome Sequencing: Not Quite Ready for Prime Time? Genetics Vanderperre B, Lucier JF, Bissonnette C, Motard J, Tremblay G, Vanderperre S, Wisztorski M, Salzet M, Boisvert FM, Roucou X. Direct detection of alternative open reading frames translation products in human significantly expands the proteome. PLoS […]
Stem cells A young scientist in Japan has found a simple approach to make totipotent stem cells by lowering the pH. Stimulus-triggered fate conversion of somatic cells into pluripotency. Nature Bidirectional developmental potential in reprogrammed cells with acquired pluripotency. Nature Cell biology: Potency unchained. Nature commentary BBC news: Stem cell ‘major discovery’ claimed Boston Globe: […]
Neuroscience Widmann A, Schröger E. Filter effects and filter artifacts in the analysis of electrophysiological data. Front Psychol. 2012 Jul 9;3:233. doi: 10.3389/fpsyg.2012.00233. eCollection 2012. PubMed PMID: 22787453; PubMed Central PMCID: PMC3391960. Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK. Microbiota modulate behavioral […]
Genomics Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013 Oct 21;14(10):R115. [Epub ahead of print] PubMed PMID: 24138928. News coverage: Scientists Discover New Biological Clock With Age-Measuring Potential News: FDA Tells Google-Backed 23andMe to Halt DNA Test Service Evolution Kolb AW, Ané C, Brandt CR. Using HSV-1 Genome Phylogenetics to Track Past Human […]