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Category Archives: Fai’s sharing

Fai’s scientific sharing with lab members

2015-01-10 new articles we read this week

Retinal development Masuda T, Zhang X, Berlinicke C, Wan J, Yerrabelli A, Conner EA, Kjellstrom S, Bush R, Thorgeirsson SS, Swaroop A, Chen S, Zack DJ. The Transcription Factor GTF2IRD1 Regulates the Topology and Function of Photoreceptors by Modulating Photoreceptor Gene Expression across the Retina. J Neurosci. 2014 Nov 12;34(46):15356-68. Okabe K, Kobayashi S, Yamada […]

Prof. Motokazu Tsujikawa visited the Leung Lab at Purdue University

Prof. Motokazu Tsujikawa from the Department of Ophthalmology and the Department of Visual Regenerative Medicine at the Osaka University Medical School in Japan visited Leung Lab at Purdue, Indiana University School of Medicine – Lafayette, Bindley Bioscience Center and Drug Discovery Center from 10/22 – 24, 2014. He also gave a departmental seminar on  “Retinal […]

2014-11-09 new articles we read … in a while

Cell cycle Malumbres M. Cyclin-dependent kinases. Genome Biol. 2014;15(6):122. PubMed PMID: 25180339; PubMed Central PMCID: PMC4097832. Sequencing/Disease Gilissen C, Hehir-Kwa JY, Thung DT, van de Vorst M, van Bon BW, Willemsen MH, Kwint M, Janssen IM, Hoischen A, Schenck A, Leach R, Klein R, Tearle R, Bo T, Pfundt R, Yntema HG, de Vries BB, […]

Ig Nobel prize 2014

Wonderful studies as usual! http://www.improbable.com/ig/winners/#ig2014 The 2014 Ig Nobel Winners: Banana Peels to Nasal Pork

2014-07-20 new articles we read this week

Nature’s special on “Challenges in irreproducible research” Human Behaviour/Psychology Kramer AD, Guillory JE, Hancock JT. Experimental evidence of massive-scale emotional contagion through social networks. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8788-90. doi: 10.1073/pnas.1320040111. Epub 2014 Jun 2. PubMed PMID: 24889601. This is THE controversial experiment by facebook. News coverage: Facebook emotion study […]

2014-07-05 New articles we read this week

Systems biology Levo M, Segal E. In pursuit of design principles of regulatory sequences. Nat Rev Genet. 2014 Jul;15(7):453-68. doi: 10.1038/nrg3684. Epub 2014 Jun 10. PubMed PMID: 24913666. Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev […]

Uri Alon: Why truly innovative science demands a leap into the unknown

Just saw this from a friend’s share. It is a great TED talk by Uri Alon on his experience on doing innovative science.   His work has inspired many including myself. Here are a few seminal papers by his groups. Milo R, Shen-Orr S, Itzkovitz S, Kashtan N, Chklovskii D, Alon U. Network motifs: simple […]

2014-06-21 new articles we read this week

Stem cells/ regenerative medicine Zhong X, Gutierrez C, Xue T, Hampton C, Vergara MN, Cao LH, Peters A, Park TS, Zambidis ET, Meyer JS, Gamm DM, Yau KW, Canto-Soler MV. Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat Commun. 2014 Jun 10;5:4047. doi: 10.1038/ncomms5047. PubMed PMID: 24915161. Reichman S, Terray A, […]

2014-06-07 New articles we read this week

Genome Editing Gagnon JA, Valen E, Thyme SB, Huang P, Ahkmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs. PLoS One. 2014 May 29;9(5):e98186. doi: 10.1371/journal.pone.0098186. eCollection 2014. PubMed PMID: 24873830. Hsu PD, Lander ES, Zhang F. Development and […]

2014 The Twelfth Annual USA Biology Olympiad National Finals

Fai and Prahatha led a Development and Disease Research Lab section in the 12th USA Biology Olympiad Finals at Purdue University and shared our lab research on eye drug discovery using the zebrafish model. The students also learned essential basic skills for zebrafish research. photoalbum by USA Biology Olympiad.