Zebrafish Adatto I, Krug L, Zon LI. The Red Light District and Its Effects on Zebrafish Reproduction. Zebrafish. 2016 Mar 15. [Epub ahead of print] PubMed PMID: 26978703. Brocal I, White RJ, Dooley CM, Carruthers SN, Clark R, Hall A, Busch-Nentwich EM, Stemple DL, Kettleborough RN. Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening […]
Monday, February 15, 2016
Scientific publishing Gibney E. Open journals that piggyback on arXiv gather momentum. Nature. 2016 Feb 4;530(7588):117-8. PubMed PMID: 26854297. Genome editing Wu B, Luo L, Gao XJ. Cas9-triggered chain ablation of cas9 as a gene drive brake. Nat Biotechnol. 2016 Feb 5;34(2):137-8. doi: 10.1038/nbt.3444. PubMed PMID: 26849513. Alphey L. Can CRISPR-Cas9 gene drives curb malaria? […]
Molecular Biology Weingarten-Gabbay S, Elias-Kirma S, Nir R, Gritsenko AA, Stern-Ginossar N, Yakhini Z, Weinberger A, Segal E. Comparative genetics. Systematic discovery of cap-independent translation sequences in human and viral genomes. Science. 2016 Jan 15;351(6270). pii: aad4939. doi: 10.1126/science.aad4939. Epub 2016 Jan 14. PubMed PMID: 26816383. Bernecky C, Herzog F, Baumeister W, Plitzko JM, Cramer […]
Genome Editing Bolukbasi MF, Gupta A, Oikemus S, Derr AG, Garber M, Brodsky MH, Zhu LJ, Wolfe SA. DNA-binding-domain fusions enhance the targeting range and precision of Cas9. Nat Methods. 2015 Oct 19. doi: 10.1038/nmeth.3624. [Epub ahead of print] PubMed PMID: 26480473. Thakore PI, D’Ippolito AM, Song L, Safi A, Shivakumar NK, Kabadi AM, Reddy […]
Nature’s special on “Challenges in irreproducible research” Human Behaviour/Psychology Kramer AD, Guillory JE, Hancock JT. Experimental evidence of massive-scale emotional contagion through social networks. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8788-90. doi: 10.1073/pnas.1320040111. Epub 2014 Jun 2. PubMed PMID: 24889601. This is THE controversial experiment by facebook. News coverage: Facebook emotion study […]
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Also tagged CRISPR-CAS, eye disease, funding, Genome editing, genomics, human behaviour, irreproducible research, next-generation sequencing, psychology, research career, retinal development, sequencing, stem cells, TALEN
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Systems biology Levo M, Segal E. In pursuit of design principles of regulatory sequences. Nat Rev Genet. 2014 Jul;15(7):453-68. doi: 10.1038/nrg3684. Epub 2014 Jun 10. PubMed PMID: 24913666. Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev […]
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Also tagged AIDS, animal behaviour, CRISPR-CAS, Genome editing, HIV, impact factor, induced pluripotent stem cells, morpholino, retina, retinal development, rna sequencing, RPE, stem cells, TALEN, Traditional Chinese Medicine, zebrafish
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Just saw this from a friend’s share. It is a great TED talk by Uri Alon on his experience on doing innovative science. His work has inspired many including myself. Here are a few seminal papers by his groups. Milo R, Shen-Orr S, Itzkovitz S, Kashtan N, Chklovskii D, Alon U. Network motifs: simple […]
Stem cells/ regenerative medicine Zhong X, Gutierrez C, Xue T, Hampton C, Vergara MN, Cao LH, Peters A, Park TS, Zambidis ET, Meyer JS, Gamm DM, Yau KW, Canto-Soler MV. Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCs. Nat Commun. 2014 Jun 10;5:4047. doi: 10.1038/ncomms5047. PubMed PMID: 24915161. Reichman S, Terray A, […]
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Also tagged behaviour, education, eye diseases, gene regulatory network, induced pluripotent stem cells, locomotor response, molecular biology, oxidative stress, regenerative medicine, retina, scientific career, stem cells, synthetic biology, zebrafish
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Saturday, December 28, 2013
Neuroscience Widmann A, Schröger E. Filter effects and filter artifacts in the analysis of electrophysiological data. Front Psychol. 2012 Jul 9;3:233. doi: 10.3389/fpsyg.2012.00233. eCollection 2012. PubMed PMID: 22787453; PubMed Central PMCID: PMC3391960. Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK. Microbiota modulate behavioral […]
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Also tagged biochemistry, Connectomics, CRISPR, CRISPR-CAS, development, electrophysiology, evolution, funding, gene regulatory network, genetics, Genome editing, genomics, imaging, medicine, Microscopy, neuroscience, retina, RNA-seq, stem cells, super-resolution imaging, TALEN, zebrafish
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Neuroscience Kabra M, Robie AA, Rivera-Alba M, Branson S, Branson K. JAABA: interactive machine learning for automatic annotation of animal behavior. Nat Methods. 2013 Jan;10(1):64-7. doi: 10.1038/nmeth.2281. Epub 2012 Dec 2. PubMed PMID: 23202433. Koch KW. The guanylate cyclase signaling system in zebrafish photoreceptors. FEBS Lett. 2013 May 6. doi:pii: S0014-5793(13)00318-9. 10.1016/j.febslet.2013.04.023. [Epub ahead of […]