An interesting study have reported a way that may potential help people who suffer from spinal cord injury. From the New York Times, “In Rat Experiment, New Hope for Spine Injuries“: Rats with a spinal cord injury that left their hind legs completely paralyzed learned to walk again on their own after an intensive training […]
Stem cells Chen J, Pei D. Reprogramming in suspension. Nat Methods. 2012 Apr 27;9(5):449-51. doi: 10.1038/nmeth.1989. PubMed PMID: 22543375. Genomics Clarke L, Zheng-Bradley X, Smith R, Kulesha E, Xiao C, Toneva I, Vaughan B, Preuss D, Leinonen R, Shumway M, Sherry S, Flicek P; The 1000 Genomes Project Consortium. The 1000 Genomes Project: data management […]
Neuroimaging/ Connectomics Wedeen VJ, Rosene DL, Wang R, Dai G, Mortazavi F, Hagmann P, Kaas JH, Tseng WY. The geometric structure of the brain fiber pathways. Science. 2012 Mar 30;335(6076):1628-34. PubMed PMID: 22461612. Neuroscience Rogulja D, Young MW. Control of sleep by cyclin A and its regulator. Science. 2012 Mar 30;335(6076):1617-21. PubMed PMID: 22461610. Koch […]
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Tagged behaviour, Career, Connectomics, ethics, eye disease, medicine, Neuroimaging, neuroscience, Philosophy, Social and Legel Issues, stem cells, systems biology
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Development Vogel G. Reproductive biology. Potential egg stem cells reignite debate. Science. 2012 Mar 2;335(6072):1029-30. PubMed PMID: 22383817. Scientific career Mervis J. Scientific careers. Is motherhood the biggest reason for academia’s gender imbalance? Science. 2012 Mar 2;335(6072):1030-1. PubMed PMID: 22383818. Genomics Xu X, Hou Y, Yin X, Bao L, Tang A, Song L, Li F, […]
Evolution Ramani AK, Chuluunbaatar T, Verster AJ, Na H, Vu V, Pelte N, Wannissorn N, Jiao A, Fraser AG. The majority of animal genes are required for wild-type fitness. Cell. 2012 Feb 17;148(4):792-802. PubMed PMID: 22341449. Loehlin DW, Werren JH. Evolution of shape by multiple regulatory changes to a growth gene. Science. 2012 Feb 24;335(6071):943-7. […]
Sunday, February 26, 2012
Stem cells/ regeneration Makkar RR, Smith RR, Cheng K, Malliaras K, Thomson LE, Berman D, Czer LS, Marbán L, Mendizabal A, Johnston PV, Russell SD, Schuleri KH, Lardo AC, Gerstenblith G, Marbán E. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet. 2012 Feb 13. [Epub ahead […]
Sunday, February 12, 2012
Delta-Notch Luo H, Jin K, Xie Z, Qiu F, Li S, Zou M, Cai L, Hozumi K, Shima DT, Xiang M. Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors. Proc Natl Acad Sci U S A. 2012 Feb 8. [Epub ahead of print] PubMed PMID: 22323600. Stem […]
Development Balaskas N, Ribeiro A, Panovska J, Dessaud E, Sasai N, Page KM, Briscoe J, Ribes V. Gene regulatory logic for reading the sonic hedgehog signaling gradient in the vertebrate neural tube. Cell. 2012 Jan 20;148(1-2):273-84. PubMed PMID: 22265416; PubMed Central PMCID: PMC3267043. Lassar A. Finding MyoD with a little help from my friends. Nat […]
Saturday, January 14, 2012
Retinal Development Kwan KM, Otsuna H, Kidokoro H, Carney KR, Saijoh Y, Chien CB. A complex choreography of cell movements shapes the vertebrate eye. Development. 2012 Jan;139(2):359-72. PubMed PMID: 22186726. Morgan JL, Soto F, Wong RO, Kerschensteiner D. Development of cell type-specific connectivity patterns of converging excitatory axons in the retina. Neuron. 2011 Sep 22;71(6):1014-21. […]
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Tagged education, evolution, genetics, genomics, medical research, neuroscience, retinal development, stem cells, systems biology, vision, zebrafish
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Thursday, January 5, 2012
Today there is an article published in CELL about the generation of chimeric monkey. Unlike the traditional way for generation of chimeric mouse for making transgenic animal that can utilize pluripotent stem cells or inner cell mass, the process in primates requires the usage of totipotent cells at a much earlier stage – 4-cell stage. […]