Thursday, August 24, 2017
Neuroscience Robie AA, Hirokawa J, Edwards AW, Umayam LA, Lee A, Phillips ML, Card GM, Korff W, Rubin GM, Simpson JH, Reiser MB, Branson K. Mapping the Neural Substrates of Behavior. Cell. 2017 Jul 13;170(2):393-406.e28. doi: 10.1016/j.cell.2017.06.032. PubMed PMID: 28709004. Smith K. How to map the circuits that define us. Nature. 2017 Aug 9;548(7666):150-152. doi: […]
Behaviour Palmér T, Ek F, Enqvist O, Olsson R, Åström K, Petersson P. Action sequencing in the spontaneous swimming behavior of zebrafish larvae – implications for drug development. Sci Rep. 2017 Jun 9;7(1):3191. doi: 10.1038/s41598-017-03144-7. PubMed PMID: 28600565; PubMed Central PMCID: PMC5466685. Vliet SM, Ho TC, Volz DC. Behavioral screening of the LOPAC(1280) library in […]
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Also tagged behaviour, Ecology, evolution, eye disease, genetics, Genome editing, genomics, imaging, neuroscience, Stem cell, vision
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Wednesday, August 10, 2016
Genome editing Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT. Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. Proc Natl Acad Sci U S A. 2016 Jun 20. pii: 201600582. [Epub ahead of print] PubMed PMID: 27325776. Regeneration Neves J, Zhu J, Sousa-Victor P, Konjikusic M, Riley R, […]
Genomics Bintu L, Yong J, Antebi YE, McCue K, Kazuki Y, Uno N, Oshimura M, Elowitz MB. Dynamics of epigenetic regulation at the single-cell level. Science. 2016 Feb 12;351(6274):720-4. doi: 10.1126/science.aab2956. PubMed PMID: 26912859. Commentary: Keung AJ, Khalil AS. MOLECULAR BIOLOGY. A unifying model of epigenetic regulation. Science. 2016 Feb 12;351(6274):661-2. doi: 10.1126/science.aaf1647. PubMed PMID: […]
Population Genetics Balaresque P, Poulet N, Cussat-Blanc S, Gerard P, Quintana-Murci L, Heyer E, Jobling MA. Y-chromosome descent clusters and male differential reproductive success: young lineage expansions dominate Asian pastoral nomadic populations. Eur J Hum Genet. 2015 Jan 14. doi: 10.1038/ejhg.2014.285. [Epub ahead of print] PubMed PMID: 25585703. Nature News: Genghis Khan’s genetic legacy has […]
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Also tagged 3d printing, development, evolution, genetics, Genome editing, genomics, imaging, medicine, neuroscience, population genetics, prosthetics, research career, retinal development
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Nature’s special on “Challenges in irreproducible research” Human Behaviour/Psychology Kramer AD, Guillory JE, Hancock JT. Experimental evidence of massive-scale emotional contagion through social networks. Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8788-90. doi: 10.1073/pnas.1320040111. Epub 2014 Jun 2. PubMed PMID: 24889601. This is THE controversial experiment by facebook. News coverage: Facebook emotion study […]
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Also tagged CRISPR-CAS, eye disease, Genome editing, genomics, human behaviour, irreproducible research, next-generation sequencing, psychology, research career, retinal development, sequencing, stem cells, systems biology, TALEN
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Saturday, December 28, 2013
Neuroscience Widmann A, Schröger E. Filter effects and filter artifacts in the analysis of electrophysiological data. Front Psychol. 2012 Jul 9;3:233. doi: 10.3389/fpsyg.2012.00233. eCollection 2012. PubMed PMID: 22787453; PubMed Central PMCID: PMC3391960. Hsiao EY, McBride SW, Hsien S, Sharon G, Hyde ER, McCue T, Codelli JA, Chow J, Reisman SE, Petrosino JF, Patterson PH, Mazmanian SK. Microbiota modulate behavioral […]
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Also tagged biochemistry, Connectomics, CRISPR, CRISPR-CAS, development, electrophysiology, evolution, gene regulatory network, genetics, Genome editing, genomics, imaging, medicine, Microscopy, neuroscience, retina, RNA-seq, stem cells, super-resolution imaging, systems biology, TALEN, zebrafish
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Neuroscience Cai D, Cohen KB, Luo T, Lichtman JW, Sanes JR. Improved tools for the Brainbow toolbox. Nat Methods. 2013 May 5;10(6):540-7. doi: 10.1038/nmeth.2450. Epub 2013 May 5. PubMed PMID: 23817127. Pan YA, Freundlich T, Weissman TA, Schoppik D, Wang XC, Zimmerman S, Ciruna B, Sanes JR, Lichtman JW, Schier AF. Zebrabow: multispectral cell labeling […]
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Also tagged CRISPR, CRISPR-CAS, eye disease, gene therapy, genetics, goldyTALEN, hypothesis-generating research, neuroscience, SCNT, stem cells, TALEN
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Wednesday, November 14, 2012
A colleague at Purdue puts it in perspective in a Bloomberg News article: College Costs Rise With $250,000-a-Year Bureaucrats
Having a good science education is essential for all of us, because that trains one’s critical thinking; while asking a lot more students to join the field is a whole different issue. A number of factors comes into play for one to decide whether he would want to pursue this career, including one’s personality, dedication, […]