Lau BY, Mathur P, Gould GG, Guo S. Identification of a brain center whose activity discriminates a choice behavior in zebrafish. Proc Natl Acad Sci U S A. 2011 Jan 24;. [Epub ahead of print] PMID: 21262817 [PubMed – as supplied by publisher]
Tay TL, Ronneberger O, Ryu S, Nitschke R, Driever W. Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nat Commun. 2011Jan;2:171. PubMed PMID: 21266970.
Gräff J, Tsai LH. Cognitive enhancement: A molecular memory booster. Nature. 2011 Jan 27;469(7331):474-5. PubMed PMID: 21270879.
Chen DY, Stern SA, Garcia-Osta A, Saunier-Rebori B, Pollonini G, Bambah-Mukku D, Blitzer RD, Alberini CM. A critical role for IGF-II in memory consolidation and enhancement. Nature. 2011 Jan 27;469(7331):491-7. PubMed PMID: 21270887.
Zebrafish
Gerety SS, Wilkinson DG. Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development. Dev Biol. 2010 Dec 8. [Epub ahead of print] PubMed PMID: 21145318.
Genomics
Majewski J, Pastinen T. The study of eQTL variations by RNA-seq: from SNPs to phenotypes. Trends Genet. 2010 Nov 29. [Epub ahead of print] PubMed PMID: 21122937.
Zhang Z, Pugh BF. High-Resolution Genome-wide Mapping of the Primary Structure of Chromatin. Cell. 2011 Jan 21;144(2):175-86. PubMed PMID: 21241889.
Gene regulatory network
Chu DF, Zabet NR, Hone AN. Optimal Parameter Settings for Information Processing in Gene Regulatory Networks. Biosystems. 2011 Jan 20. [Epub ahead of print] PubMed PMID: 21256918.
Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N, Yosef N, Chang CY, Shay T, Frampton GM, Drake AC, Leskov I, Nilsson B, Preffer F, Dombkowski D, Evans JW, Liefeld T, Smutko JS, Chen J, Friedman N, Young RA, Golub TR, Regev A, Ebert BL. Densely interconnected transcriptional circuits control cell States in human hematopoiesis. Cell. 2011 Jan 21;144(2):296-309. PubMed PMID: 21241896.
Grundberg E, Adoue V, Kwan T, Ge B, Duan QL, Lam KC, Koka V, Kindmark A, Weiss ST, Tantisira K, Mallmin H, Raby BA, Nilsson O, Pastinen T. Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression. PLoS Genet. 2011 Jan 20;7(1):e1001279. PubMed PMID: 21283786; PubMed Central PMCID: PMC3024267
Ethical, Social and Legal Issues
Bredenoord AL, Kroes HY, Cuppen E, Parker M, van Delden JJ. Disclosure of individual genetic data to research participants: the debate reconsidered. Trends Genet. 2010 Dec 27. [Epub ahead of print] PubMed PMID: 21190750.
Eye disease
Baye LM, Patrinostro X, Swaminathan S, Beck JS, Zhang Y, Stone EM, Sheffield VC, Slusarski DC. The N-terminal region of CEP290 restores vision in a zebrafish model of human blindness. Hum Mol Genet. 2011 Jan 21;. [Epub ahead of print]
Disease
Liu S, Leach SD. Zebrafish models for cancer. Annu Rev Pathol. 2011 Feb 28;6:71-93. PubMed PMID: 21261518.
Brg1 & Wnt
Griffin CT, Curtis CD, Davis RB, Muthukumar V, Magnuson T. The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels. Proc Natl Acad Sci U S A. 2011 Jan 24. [Epub ahead of print] PubMed PMID: 21262838.
Cell biology
Ikeda K, Semenova I, Zhapparova O, Rodionov V. Melanophores for microtubule dynamics and motility assays. Methods Cell Biol. 2010;97:401-14. Review. PubMed PMID: 20719282.
Pagh-Roehl K, Wang E, Burnside B. Posttranslational modifications of tubulin in teleost photoreceptor cytoskeletons. Cell Mol Neurobiol. 1991 Dec;11(6):593-610. PubMed PMID: 1782652.
Funding
Macilwain C. Funding in 2011: East heats up as west cools down. Cell. 2011 Jan 21;144(2):167-9. PubMed PMID: 21241886.
Filed in journal watch||Comments Off on 2011-02-05 New articles we read this week
Bravo HC, Irizarry RA. Model-based quality assessment and base-calling for second-generation sequencing data. Biometrics. 2010 Sep;66(3):665-74. doi: 10.1111/j.1541-0420.2009.01353.x. Review. PubMed PMID: 19912177; PubMed Central PMCID: PMC2888717.
Taub MA, Corrada Bravo H, Irizarry RA. Overcoming bias and systematic errors in next generation sequencing data. Genome Med. 2010 Dec 10;2(12):87. [Epub ahead of print] PubMed PMID: 21144010.
Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nürnberger A, Schmidt K, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M,
Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, Garcia-Calero E, Kruse S, Uhr M, Kauck C, Feng G, Milyaev N, Ong CK, Kumar L, Lam M, Semple CA, Gyenesei A, Mundlos S, Radelof U, Lehrach H, Sarmientos P, Reymond A, Davidson DR, Dollé P, Antonarakis SE, Yaspo ML, Martinez S, Baldock RA, Eichele G, Ballabio A. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011 Jan 18;9(1):e1000582. PubMed PMID: 21267068.
Genome-Wide Association Study
Shields R. Common disease: are causative alleles common or rare? PLoS Biol. 2011 Jan 18;9(1):e1001009. PubMed PMID: 21267067.
Goldstein DB. The importance of synthetic associations will only be resolved empirically. PLoS Biol. 2011 Jan 18;9(1):e1001008. PubMed PMID: 21267066.
Anderson CA, Soranzo N, Zeggini E, Barrett JC. Synthetic associations are unlikely to account for many common disease genome-wide association signals. PLoS Biol. 2011 Jan 18;9(1):e1000580. PubMed PMID: 21267062.
Wray NR, Purcell SM, Visscher PM. Synthetic Associations Created by Rare Variants Do Not Explain Most GWAS Results. PLoS Biol. 2011 Jan 18;9(1):e1000579. PubMed PMID: 21267061.
Systems Biology
Snijder B, Pelkmans L. Origins of regulated cell-to-cell variability. Nat Rev Mol Cell Biol. 2011 Feb;12(2):119-25. Epub 2011 Jan 12. PubMed PMID: 21224886.
Retina & Retinal Pigment Epithelium
Choi RY, Engbretson GA, Solessio E, Jones GA, Coughlin A, Aleksic I, Zuber ME. Cone Degeneration Following Rod Ablation in a Reversible Model of Retinal Degeneration. Invest Ophthalmol Vis Sci. 2010 Aug 18. [Epub ahead of print] PubMed PMID: 20720220.
Dwyer MA, Kazmin D, Hu P, McDonnell DP, Malek G. Research Resource: Nuclear Receptor Atlas of Human Retinal Pigment Epithelial Cells: Potential Relevance to Age-Related Macular Degeneration. Mol Endocrinol. 2011 Jan 14. [Epub ahead of print] PubMed PMID: 21239617.
Zebrafish
Sánchez-Vázquez FJ, Terry MI, Felizardo VO, Vera LM. Daily Rhythms of Toxicity and Effectiveness of Anesthetics (MS222 and Eugenol) in Zebrafish (Danio Rerio). Chronobiol Int. 2011 Mar.;28(2):109-117. PubMed PMID: 21231872.
Medicine
The Lancet. Religion, organ transplantation, and the definition of death. Lancet. 2011 Jan 22;377(9762):271. PubMed PMID: 21256368.
Caleb: I saw it I saw it I saw it! Jin: No, you don't.
Zeran: I can work hard even in the dark! I can work hard even without eating! I can work hard even without drinking! I can work hard even without sleeping! I can... I can ... I can... who am I?
Filed in fun, pictures||Comments Off on Dedicated Purdue students who worked in darkness to bring lights to the world
Bansal V, Tewhey R, Topol EJ, Schork NJ. The next phase in human genetics. Nat Biotechnol. 2011 Jan;29(1):38-9. PubMed PMID: 21221098.
Li MA, Bradley A. Crafting rat genomes with zinc fingers. Nat Biotechnol. 2011 Jan;29(1):39-41. PubMed PMID: 21221099.
Fan HC, Wang J, Potanina A, Quake SR. Whole-genome molecular haplotyping of single cells. Nat Biotechnol. 2011 Jan;29(1):51-7. Epub 2010 Dec 19. PubMed PMID: 21170043.
Kitzman JO, Mackenzie AP, Adey A, Hiatt JB, Patwardhan RP, Sudmant PH, Ng SB, Alkan C, Qiu R, Eichler EE, Shendure J. Haplotype-resolved genome sequencing of a Gujarati Indian individual. Nat Biotechnol. 2011 Jan;29(1):59-63. Epub 2010 Dec 19. PubMed PMID: 21170042.
Cui X, Ji D, Fisher DA, Wu Y, Briner DM, Weinstein EJ. Targeted integration in rat and mouse embryos with zinc-finger nucleases. Nat Biotechnol. 2011 Jan;29(1):64-7. Epub 2010 Dec 12. PubMed PMID: 21151125.
Auer PL, Doerge RW. Statistical design and analysis of RNA sequencing data. Genetics. 2010 Jun;185(2):405-16. Epub 2010 May 3. PubMed PMID: 20439781; PubMed Central PMCID: PMC2881125.
Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010 Jan 1;26(1):139-40. Epub 2009 Nov 11. PubMed PMID: 19910308; PubMed Central PMCID: PMC2796818.
Eye disease
Asherie N. Blind attraction: The mechanism of an inherited congenital cataract. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):437-8. Epub 2010 Dec 28. PubMed PMID: 21189296.
Retina
Morris AC, Forbes-Osborne MA, Pillai LS, Fadool JM. Microarray Analysis of XOPS-mCFP Zebrafish Retina Identifies Genes Associated with Rod Photoreceptor Degeneration and Regeneration. Invest Ophthalmol Vis Sci. 2011 Jan 7. [Epub ahead of print] PubMed PMID: 21217106.
Buske P, Galle J, Barker N, Aust G, Clevers H, Loeffler M. A comprehensive model of the spatio-temporal stem cell and tissue organisation in the intestinal crypt. PLoS Comput Biol. 2011 Jan 6;7(1):e1001045. PubMed PMID: 21253562.
Gene regulatory network
Shou C, Bhardwaj N, Lam HY, Yan KK, Kim PM, Snyder M, Gerstein MB. Measuring the evolutionary rewiring of biological networks. PLoS Comput Biol. 2011 Jan 6;7(1):e1001050. PubMed PMID: 21253555.
French L, Pavlidis P. Relationships between Gene Expression and Brain Wiring in the Adult Rodent Brain. PLoS Comput Biol. 2011 Jan 6;7(1):e1001049. PubMed PMID: 21253556.
Neuroscience
Kohl J, Jefferis GS. Neuroanatomy: decoding the fly brain. Curr Biol. 2011 Jan 11;21(1):R19-20. PubMed PMID: 21215929.
Chiang AS, Lin CY, Chuang CC, Chang HM, Hsieh CH, Yeh CW, Shih CT, Wu JJ, Wang GT, Chen YC, Wu CC, Chen GY, Ching YT, Lee PC, Lin CY, Lin HH, Wu CC, Hsu HW, Huang YA, Chen JY, Chiang HJ, Lu CF, Ni RF, Yeh CY, Hwang JK. Three-Dimensional Reconstruction of Brain-wide Wiring Networks in Drosophila at Single-Cell Resolution. Curr Biol. 2011 Jan 11;21(1):1-11. Epub 2010 Dec 2. PubMed PMID: 21129968.
Development
Del Álamo D, Rouault H, Schweisguth F. Mechanism and Significance of cis-Inhibition in Notch Signalling. Curr Biol. 2011 Jan 11;21(1):R40-7. PubMed PMID: 21215938.
Filed in journal watch||Comments Off on 2011-01-22 New articles we read this week
Kinkhabwala A, Riley M, Koyama M, Monen J, Satou C, Kimura Y, Higashijima SI, Fetcho J. A structural and functional ground plan for neurons in the hindbrain of zebrafish. Proc Natl Acad Sci U S A. 2011 Jan 3. [Epub ahead of print] PubMed PMID: 21199947.
Koyama M, Kinkhabwala A, Satou C, Higashijima SI, Fetcho J. Mapping a sensory-motor network onto a structural and functional ground plan in the hindbrain. Proc Natl Acad Sci U S A. 2011 Jan 3. [Epub ahead of print] PubMed PMID: 21199937.
Suchow JW, Alvarez GA. Motion Silences Awareness of Visual Change. Curr Biol. 2011 Jan 5. [Epub ahead of print] PubMed PMID: 21215632.
Don’t forget to check this video out before you read the article!
Cell Biology
Salinas PC. Modulation of the microtubule cytoskeleton: a role for a divergent canonical Wnt pathway. Trends Cell Biol. 2007 Jul;17(7):333-42. Epub 2007 Jul 20. Review. PubMed PMID: 17643305.
Fussner E, Ching RW, Bazett-Jones DP. Living without 30nm chromatin fibers. Trends Biochem Sci. 2011 Jan;36(1):1-6. PubMed PMID: 20926298.
Genomics
Balasubramanian S, Habegger L, Frankish A, Macarthur DG, Harte R, Tyler-Smith C, Harrow J, Gerstein M. Gene inactivation and its implications for annotation inthe era of personal genomics. Genes Dev. 2011 Jan 1;25(1):1-10. PubMed PMID: 21205862.
Miller C, Schwalb B, Maier K, Schulz D, Dümcke S, Zacher B, Mayer A, Sydow J, Marcinowski L, Dölken L, Martin DE, Tresch A, Cramer P. Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast. Mol Syst Biol. 2011 Jan 4;7:458. PubMed PMID: 21206491.
Eye disease
Li X, Li W, Dai X, Kong F, Zheng Q, Zhou X, Lü F, Chang B, Rohrer B, Hauswirth WW, Qu J, Pang JJ. Gene Therapy Rescues Cone Structure and Function in the 3-Month-Old rd12 Mouse: A Model for Midcourse RPE65 Leber Congenital Amaurosis. Invest Ophthalmol Vis Sci. 2011 Jan 5;52(1):7-15. Print 2011. PubMed PMID: 21169527.
Weleber RG, Michaelides M, Trzupek KM, Stover NB, Stone EM. The Phenotype of Severe Early Childhood Onset Retinal Dystrophy (SECORD) from Mutation of RPE65 and Differentiation from Leber Congenital Amaurosis. Invest Ophthalmol Vis Sci. 2011 Jan 5;52(1):292-302. Print 2011. PubMed PMID: 20811047.
Development
Sepich DS, Usmani M, Pawlicki S, Solnica-Krezel L. Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements. Development. 2011 Feb;138(3):543-52. PubMed PMID: 21205798.
Filed in Fai's sharing||Comments Off on 2011-01-15 New articles we read this week.
Easterlin RA, McVey LA, Switek M, Sawangfa O, Zweig JS. The happiness-income paradox revisited. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22463-8. Epub 2010 Dec 13. PubMed PMID: 21149705.
Genetics
Toettcher JE, Voigt CA, Weiner OD, Lim WA. The promise of optogenetics in cell biology: interrogating molecular circuits in space and time. Nat Methods. 2011 Jan;8(1):35-8. Epub 2010 Dec 20. PubMed PMID: 21191370.
Gradinaru V, Mogri M, Thompson KR, Henderson JM, Deisseroth K. Optical deconstruction of parkinsonian neural circuitry. Science. 2009 Apr 17;324(5925):354-9. Epub 2009 Mar 19. PubMed PMID: 19299587.
Gene Regulatory Network/ Development
Saudemont A, Haillot E, Mekpoh F, Bessodes N, Quirin M, Lapraz F, Duboc V, Röttinger E, Range R, Oisel A, Besnardeau L, Wincker P, Lepage T. Ancestral Regulatory Circuits Governing Ectoderm Patterning Downstream of Nodal and BMP2/4 Revealed by Gene Regulatory Network Analysis in an Echinoderm. PLoS Genet. 2010 Dec 23;6(12):e1001259. PubMed PMID: 21203442; PubMed Central PMCID: PMC3009687.
Hurtado A, Holmes KA, Ross-Innes CS, Schmidt D, Carroll JS. FOXA1 is a key determinant of estrogen receptor function and endocrine response. Nat Genet. 2010 Dec 12. [Epub ahead of print] PubMed PMID: 21151129.
Cell cycle
Coudreuse D, Nurse P. Driving the cell cycle with a minimal CDK control network. Nature. 2010 Dec 23;468(7327):1074-9. PubMed PMID: 21179163.
Filed in journal watch||Comments Off on 2011-01-08 articles we read this week
Teenager: “Please, Mom and Dad, just let me do this, and I promise that I will take full responsibility for it.”
Parent: “Do you realize that taking full responsibility means that if it backfires and goes wrong, you will own up to it, pay back whatever it takes to make up for it going wrong and learn from it so that it doesn’t happen again?”
Teenager: “I didn’t agree to that.”
Parent: “Well, then what do you think taking full responsibility means?”
Teenager: “That if it goes wrong, I will say, ‘I’m sorry.'”
Gene regulatory network/ signal transduction/ Systems biology
Davidson EH. Emerging properties of animal gene regulatory networks. Nature. 2010 Dec 16;468(7326):911-20. PubMed PMID: 21164479.
Booth LN, Tuch BB, Johnson AD. Intercalation of a new tier of transcription regulation into an ancient circuit. Nature. 2010 Dec 16;468(7326):959-63. PubMed PMID: 21164485.
Kolodkin AN, Bruggeman FJ, Plant N, Moné MJ, Bakker BM, Campbell MJ, van Leeuwen JP, Carlberg C, Snoep JL, Westerhoff HV. Design principles of nuclear receptor signaling: how complex networking improves signal transduction. Mol Syst Biol. 2010 Dec 21;6:446. PubMed PMID: 21179018.
Siryaporn A, Perchuk BS, Laub MT, Goulian M. Evolving a robust signal transduction pathway from weak cross-talk. Mol Syst Biol. 2010 Dec 21;6:452. PubMed PMID: 21179024.
Inouye M, Kettunen J, Soininen P, Silander K, Ripatti S, Kumpula LS, Hämäläinen E, Jousilahti P, Kangas AJ, Männistö S, Savolainen MJ, Jula A, Leiviskä J, Palotie A, Salomaa V, Perola M, Ala-Korpela M, Peltonen L. Metabonomic, transcriptomic, and genomic variation of a population cohort. Mol Syst Biol. 2010 Dec 21;6:441. PubMed PMID: 21179014.
Oshlack A, Robinson MD, Young MD. From RNA-seq reads to differential expression results. Genome Biol. 2010 Dec 22;11(12):220. [Epub ahead of print] PubMed PMID: 21176179.
Humanities
Bohannon J. Digital data. Google opens books to new cultural studies. Science. 2010 Dec 17;330(6011):1600. PubMed PMID: 21163974.
Michel JB, Shen YK, Aiden AP, Veres A, Gray MK; The Google Books Team, Pickett JP, Hoiberg D, Clancy D, Norvig P, Orwant J, Pinker S, Nowak MA, Aiden EL. Quantitative Analysis of Culture Using Millions of Digitized Books. Science. 2010 Dec 16. [Epub ahead of print] PubMed PMID: 21163965.
Collins F. The bridge between lab and clinic. Nature. 2010 Dec 16;468(7326):877. PubMed PMID: 21164451.
British Medical Journal Christmas series
Heinrich H, Goetze O, Menne D, Iten PX, Fruehauf H, Vavricka SR, Schwizer W, Fried M, Fox M. Effect on gastric function and symptoms of drinking wine, black tea, or schnapps with a Swiss cheese fondue: randomised controlled crossover trial. BMJ. 2010 Dec 14;341:c6731. doi: 10.1136/bmj.c6731. PubMed PMID: 21156747.
Rothberg MB, Arora A, Hermann J, Kleppel R, Marie PS, Visintainer P. Phantom vibration syndrome among medical staff: a cross sectional survey. BMJ. 2010 Dec 15;341:c6914. doi: 10.1136/bmj.c6914. PubMed PMID: 21159761.
McCain RS, Harris AR, McCallion K, Campbell WJ, Kirk SJ. The barrier method as a new tool to assist in career selection: covert observational study. BMJ. 2010 Dec 15;341:c6968. doi: 10.1136/bmj.c6968. PubMed PMID: 21159762; PubMed Central PMCID: PMC3002171.
Axelsson J, Sundelin T, Ingre M, Van Someren EJ, Olsson A, Lekander M. Beauty sleep: experimental study on the perceived health and attractiveness of sleep deprived people. BMJ. 2010 Dec 14;341:c6614. doi: 10.1136/bmj.c6614. PubMed PMID: 21156746.
Solomon AW, Kirwan CJ, Alexander ND, Nimako K, Jurukov A, Forth RJ, Rahman TM; Prospective Analysis of Renal Compensation for Hypohydration in Exhausted Doctors
(PARCHED) Investigators. Urine output on an intensive care unit: case-control study. BMJ. 2010 Dec 14;341:c6761. doi: 10.1136/bmj.c6761. PubMed PMID: 21156738; PubMed Central PMCID: PMC3001704.
Hansen CS, Faerch LH, Kristensen PL. Testing the validity of the Danish urban myth that alcohol can be absorbed through feet: open labelled self experimental study. BMJ. 2010 Dec 14;341:c6812. doi: 10.1136/bmj.c6812. PubMed PMID: 21156749.
Retina
Menger GJ, Koke JR, Cahill GM. Diurnal and circadian retinomotor movements in zebrafish. Vis Neurosci. 2005 Mar-Apr;22(2):203-9. PubMed PMID: 15935112.
Tsujimura T, Hosoya T, Kawamura S. A single enhancer regulating the differential expression of duplicated red-sensitive opsin genes in zebrafish. PLoS Genet. 2010 Dec 16;6(12):e1001245. PubMed PMID: 21187910; PubMed Central PMCID: PMC3002997.
Fish
Li S, Pozhitkov A, Ryan RA, Manning CS, Brown-Peterson N, Brouwer M. Constructing a fish metabolic network model. Genome Biol. 2010 Nov 29;11(11):R115. [Epub ahead of print] PubMed PMID: 21114829.
Filed in journal watch||Comments Off on 2011-01-02 New articles we read this week