Leung Lab Blog

Gene regulatory network/ signal transduction/ Systems biology

1. Davidson EH. Emerging properties of animal gene regulatory networks. Nature. 2010 Dec 16;468(7326):911-20. PubMed PMID: 21164479.
2. Booth LN, Tuch BB, Johnson AD. Intercalation of a new tier of transcription regulation into an ancient circuit. Nature. 2010 Dec 16;468(7326):959-63. PubMed PMID: 21164485.
3. Kolodkin AN, Bruggeman FJ, Plant N, Moné MJ, Bakker BM, Campbell MJ, van Leeuwen JP, Carlberg C, Snoep JL, Westerhoff HV. Design principles of nuclear receptor signaling: how complex networking improves signal transduction. Mol Syst Biol. 2010 Dec 21;6:446. PubMed PMID: 21179018.
4. Siryaporn A, Perchuk BS, Laub MT, Goulian M. Evolving a robust signal transduction pathway from weak cross-talk. Mol Syst Biol. 2010 Dec 21;6:452. PubMed PMID: 21179024.
5. Inouye M, Kettunen J, Soininen P, Silander K, Ripatti S, Kumpula LS, Hämäläinen E, Jousilahti P, Kangas AJ, Männistö S, Savolainen MJ, Jula A, Leiviskä J, Palotie A, Salomaa V, Perola M, Ala-Korpela M, Peltonen L. Metabonomic, transcriptomic, and genomic variation of a population cohort. Mol Syst Biol. 2010 Dec 21;6:441. PubMed PMID: 21179014.
6. Oshlack A, Robinson MD, Young MD. From RNA-seq reads to differential expression results. Genome Biol. 2010 Dec 22;11(12):220. [Epub ahead of print] PubMed PMID: 21176179.

Humanities

1. Bohannon J. Digital data. Google opens books to new cultural studies. Science. 2010 Dec 17;330(6011):1600. PubMed PMID: 21163974.
2. Michel JB, Shen YK, Aiden AP, Veres A, Gray MK; The Google Books Team, Pickett JP, Hoiberg D, Clancy D, Norvig P, Orwant J, Pinker S, Nowak MA, Aiden EL. Quantitative Analysis of Culture Using Millions of Digitized Books. Science. 2010 Dec 16. [Epub ahead of print] PubMed PMID: 21163965.
   • They called this project culturomics, see http://www.culturomics.org

Medicine

1. Collins F. The bridge between lab and clinic. Nature. 2010 Dec 16;468(7326):877. PubMed PMID: 21164451.
2. British Medical Journal Christmas series
   • Heinrich H, Goetze O, Menne D, Iten PX, Fruehauf H, Vavricka SR, Schwizer W, Fried M, Fox M. Effect on gastric function and symptoms of drinking wine, black tea, or schnapps with a Swiss cheese fondue: randomised controlled crossover trial. BMJ. 2010 Dec 14;341:c6731. doi: 10.1136/bmj.c6731. PubMed PMID: 21156747.
   • Rothberg MB, Arora A, Hermann J, Kleppel R, Marie PS, Visintainer P. Phantom vibration syndrome among medical staff: a cross sectional survey. BMJ. 2010 Dec 15;341:c6914. doi: 10.1136/bmj.c6914. PubMed PMID: 21159761.
   • McCain RS, Harris AR, McCallion K, Campbell WJ, Kirk SJ. The barrier method as a new tool to assist in career selection: covert observational study. BMJ. 2010 Dec 15;341:c6968. doi: 10.1136/bmj.c6968. PubMed PMID: 21159762; PubMed Central PMCID: PMC3002171.
   • Axelsson J, Sundelin T, Ingre M, Van Someren EJ, Olsson A, Lekander M. Beauty sleep: experimental study on the perceived health and attractiveness of sleep deprived people. BMJ. 2010 Dec 14;341:c6614. doi: 10.1136/bmj.c6614. PubMed PMID: 21156746.
   • Solomon AW, Kirwan CJ, Alexander ND, Nimako K, Jurukov A, Forth RJ, Rahman TM; Prospective Analysis of Renal Compensation for Hypohydration in Exhausted Doctors
     (PARCHED) Investigators. Urine output on an intensive care unit: case-control study. BMJ. 2010 Dec 14;341:c6761. doi: 10.1136/bmj.c6761. PubMed PMID: 21156738; PubMed Central PMCID: PMC3001704.
   • Hansen CS, Faerch LH, Kristensen PL. Testing the validity of the Danish urban myth that alcohol can be absorbed through feet: open labelled self experimental study. BMJ. 2010 Dec 14;341:c6812. doi: 10.1136/bmj.c6812. PubMed PMID: 21156749.

Retina

1. Menger GJ, Koke JR, Cahill GM. Diurnal and circadian retinomotor movements in zebrafish. Vis Neurosci. 2005 Mar-Apr;22(2):203-9. PubMed PMID: 15935112.
2. Tsujimura T, Hosoya T, Kawamura S. A single enhancer regulating the differential expression of duplicated red-sensitive opsin genes in zebrafish. PLoS Genet. 2010 Dec 16;6(12):e1001245. PubMed PMID: 21187910; PubMed Central PMCID: PMC3002997.

Fish

1. Li S, Pozhitkov A, Ryan RA, Manning CS, Brown-Peterson N, Brouwer M. Constructing a fish metabolic network model. Genome Biol. 2010 Nov 29;11(11):R115. [Epub ahead of print] PubMed PMID: 21114829.