Leung Lab Blog

Genetics/Genomics

1. Bansal V, Tewhey R, Topol EJ, Schork NJ. The next phase in human genetics. Nat Biotechnol. 2011 Jan;29(1):38-9. PubMed PMID: 21221098.
2. Li MA, Bradley A. Crafting rat genomes with zinc fingers. Nat Biotechnol. 2011 Jan;29(1):39-41. PubMed PMID: 21221099.
3. Fan HC, Wang J, Potanina A, Quake SR. Whole-genome molecular haplotyping of single cells. Nat Biotechnol. 2011 Jan;29(1):51-7. Epub 2010 Dec 19. PubMed PMID: 21170043.
4. Kitzman JO, Mackenzie AP, Adey A, Hiatt JB, Patwardhan RP, Sudmant PH, Ng SB,  Alkan C, Qiu R, Eichler EE, Shendure J. Haplotype-resolved genome sequencing of a Gujarati Indian individual. Nat Biotechnol. 2011 Jan;29(1):59-63. Epub 2010 Dec 19. PubMed PMID: 21170042.
5. Cui X, Ji D, Fisher DA, Wu Y, Briner DM, Weinstein EJ. Targeted integration in rat and mouse embryos with zinc-finger nucleases. Nat Biotechnol. 2011 Jan;29(1):64-7. Epub 2010 Dec 12. PubMed PMID: 21151125.
6. Auer PL, Doerge RW. Statistical design and analysis of RNA sequencing data. Genetics. 2010 Jun;185(2):405-16. Epub 2010 May 3. PubMed PMID: 20439781; PubMed Central PMCID: PMC2881125.
7. Robinson MD, McCarthy DJ, Smyth GK. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data. Bioinformatics. 2010 Jan 1;26(1):139-40. Epub 2009 Nov 11. PubMed PMID: 19910308; PubMed Central PMCID: PMC2796818.

Eye disease

1. Asherie N. Blind attraction: The mechanism of an inherited congenital cataract. Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):437-8. Epub 2010 Dec 28. PubMed PMID: 21189296.

Retina

1. Morris AC, Forbes-Osborne MA, Pillai LS, Fadool JM. Microarray Analysis of XOPS-mCFP Zebrafish Retina Identifies Genes Associated with Rod Photoreceptor Degeneration and Regeneration. Invest Ophthalmol Vis Sci. 2011 Jan 7. [Epub ahead of print] PubMed PMID: 21217106.

Computational Biology/ Systems Biology

1. Mak HC. Trends in computational biology-2010. Nat Biotechnol. 2011 Jan;29(1):45. PubMed PMID: 21221102.
2. Buske P, Galle J, Barker N, Aust G, Clevers H, Loeffler M. A comprehensive model of the spatio-temporal stem cell and tissue organisation in the intestinal crypt. PLoS Comput Biol. 2011 Jan 6;7(1):e1001045. PubMed PMID: 21253562.

Gene regulatory network

1. Shou C, Bhardwaj N, Lam HY, Yan KK, Kim PM, Snyder M, Gerstein MB. Measuring the evolutionary rewiring of biological networks. PLoS Comput Biol. 2011 Jan 6;7(1):e1001050. PubMed PMID: 21253555.
2. French L, Pavlidis P. Relationships between Gene Expression and Brain Wiring in the Adult Rodent Brain. PLoS Comput Biol. 2011 Jan 6;7(1):e1001049. PubMed PMID: 21253556.

Neuroscience

1. Kohl J, Jefferis GS. Neuroanatomy: decoding the fly brain. Curr Biol. 2011 Jan 11;21(1):R19-20. PubMed PMID: 21215929.
2. Chiang AS, Lin CY, Chuang CC, Chang HM, Hsieh CH, Yeh CW, Shih CT, Wu JJ, Wang GT, Chen YC, Wu CC, Chen GY, Ching YT, Lee PC, Lin CY, Lin HH, Wu CC, Hsu HW, Huang YA, Chen JY, Chiang HJ, Lu CF, Ni RF, Yeh CY, Hwang JK. Three-Dimensional Reconstruction of Brain-wide Wiring Networks in Drosophila at Single-Cell Resolution. Curr Biol. 2011 Jan 11;21(1):1-11. Epub 2010 Dec 2. PubMed PMID: 21129968.

Development

1. Del Álamo D, Rouault H, Schweisguth F. Mechanism and Significance of cis-Inhibition in Notch Signalling. Curr Biol. 2011 Jan 11;21(1):R40-7. PubMed PMID: 21215938.