Leung Lab Blog

Lab life

1. The care and maintenance of your adviser

Neuroscience

1. Lau BY, Mathur P, Gould GG, Guo S. Identification of a brain center whose activity discriminates a choice behavior in zebrafish. Proc Natl Acad Sci U S A. 2011 Jan 24;. [Epub ahead of print] PMID: 21262817 [PubMed – as supplied by publisher]
2. Tay TL, Ronneberger O, Ryu S, Nitschke R, Driever W. Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nat Commun. 2011Jan;2:171. PubMed PMID: 21266970.
3. Gräff J, Tsai LH. Cognitive enhancement: A molecular memory booster. Nature. 2011 Jan 27;469(7331):474-5. PubMed PMID: 21270879.
4. Chen DY, Stern SA, Garcia-Osta A, Saunier-Rebori B, Pollonini G, Bambah-Mukku D, Blitzer RD, Alberini CM. A critical role for IGF-II in memory consolidation and enhancement. Nature. 2011 Jan 27;469(7331):491-7. PubMed PMID: 21270887.

Zebrafish

1. Gerety SS, Wilkinson DG. Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development. Dev Biol. 2010 Dec 8. [Epub ahead of print] PubMed PMID: 21145318.

Genomics

1. Majewski J, Pastinen T. The study of eQTL variations by RNA-seq: from SNPs to phenotypes. Trends Genet. 2010 Nov 29. [Epub ahead of print] PubMed PMID: 21122937.
2. Zhang Z, Pugh BF. High-Resolution Genome-wide Mapping of the Primary Structure of Chromatin. Cell. 2011 Jan 21;144(2):175-86. PubMed PMID: 21241889.

Gene regulatory network

1. Chu DF, Zabet NR, Hone AN. Optimal Parameter Settings for Information Processing in Gene Regulatory Networks. Biosystems. 2011 Jan 20. [Epub ahead of print] PubMed PMID: 21256918.
2. Novershtern N, Subramanian A, Lawton LN, Mak RH, Haining WN, McConkey ME, Habib N, Yosef N, Chang CY, Shay T, Frampton GM, Drake AC, Leskov I, Nilsson B, Preffer F, Dombkowski D, Evans JW, Liefeld T, Smutko JS, Chen J, Friedman N, Young RA, Golub TR, Regev A, Ebert BL. Densely interconnected transcriptional circuits control cell States in human hematopoiesis. Cell. 2011 Jan 21;144(2):296-309. PubMed PMID: 21241896.
3. Grundberg E, Adoue V, Kwan T, Ge B, Duan QL, Lam KC, Koka V, Kindmark A, Weiss ST, Tantisira K, Mallmin H, Raby BA, Nilsson O, Pastinen T. Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression. PLoS Genet. 2011 Jan 20;7(1):e1001279. PubMed PMID: 21283786; PubMed Central PMCID: PMC3024267

Ethical, Social and Legal Issues

1. Bredenoord AL, Kroes HY, Cuppen E, Parker M, van Delden JJ. Disclosure of individual genetic data to research participants: the debate reconsidered. Trends Genet. 2010 Dec 27. [Epub ahead of print] PubMed PMID: 21190750.

Eye disease

1. Baye LM, Patrinostro X, Swaminathan S, Beck JS, Zhang Y, Stone EM, Sheffield VC, Slusarski DC.  The N-terminal region of CEP290 restores vision in a zebrafish model of human blindness. Hum Mol Genet. 2011 Jan 21;. [Epub ahead of print]

Disease

1. Liu S, Leach SD. Zebrafish models for cancer. Annu Rev Pathol. 2011 Feb 28;6:71-93. PubMed PMID: 21261518.

Brg1 & Wnt

1. Griffin CT, Curtis CD, Davis RB, Muthukumar V, Magnuson T. The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels.  Proc Natl Acad Sci U S A. 2011 Jan 24. [Epub ahead of print] PubMed PMID: 21262838.

Cell biology

1. Ikeda K, Semenova I, Zhapparova O, Rodionov V. Melanophores for microtubule dynamics and motility assays. Methods Cell Biol. 2010;97:401-14. Review. PubMed PMID: 20719282.
2. Pagh-Roehl K, Wang E, Burnside B. Posttranslational modifications of tubulin in teleost photoreceptor cytoskeletons. Cell Mol Neurobiol. 1991 Dec;11(6):593-610. PubMed PMID: 1782652.

Funding

1. Macilwain C. Funding in 2011: East heats up as west cools down. Cell. 2011 Jan 21;144(2):167-9. PubMed PMID: 21241886.