Neuroimaging/ Connectomics Wedeen VJ, Rosene DL, Wang R, Dai G, Mortazavi F, Hagmann P, Kaas JH, Tseng WY. The geometric structure of the brain fiber pathways. Science. 2012 Mar 30;335(6076):1628-34. PubMed PMID: 22461612. Neuroscience Rogulja D, Young MW. Control of sleep by cyclin A and its regulator. Science. 2012 Mar 30;335(6076):1617-21. PubMed PMID: 22461610. Koch […]
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Also tagged behaviour, Career, Connectomics, ethics, eye disease, medicine, Neuroimaging, neuroscience, Philosophy, Social and Legel Issues, systems biology
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In my last post, I provided several links to general introductions of stem cells. In this post, I will share several documentaries that show how bad people are taking advantage of desperate patients who have heard stem cells therapy may give them a last hope. II. Desperate patients and people who take advantage of their […]
Evolution Ramani AK, Chuluunbaatar T, Verster AJ, Na H, Vu V, Pelte N, Wannissorn N, Jiao A, Fraser AG. The majority of animal genes are required for wild-type fitness. Cell. 2012 Feb 17;148(4):792-802. PubMed PMID: 22341449. Loehlin DW, Werren JH. Evolution of shape by multiple regulatory changes to a growth gene. Science. 2012 Feb 24;335(6071):943-7. […]
Sunday, February 26, 2012
Stem cells/ regeneration Makkar RR, Smith RR, Cheng K, Malliaras K, Thomson LE, Berman D, Czer LS, Marbán L, Mendizabal A, Johnston PV, Russell SD, Schuleri KH, Lardo AC, Gerstenblith G, Marbán E. Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet. 2012 Feb 13. [Epub ahead […]
Sunday, February 12, 2012
Delta-Notch Luo H, Jin K, Xie Z, Qiu F, Li S, Zou M, Cai L, Hozumi K, Shima DT, Xiang M. Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors. Proc Natl Acad Sci U S A. 2012 Feb 8. [Epub ahead of print] PubMed PMID: 22323600. Stem […]
Wednesday, January 25, 2012
From Washington Post: For the first time, an experimental treatment made from human embryonic stem cells has shown evidence of helping someone, partially restoring sight to two people suffering from slowly progressing forms of blindness. In short, the authors of this study that is just published in Lancet differentiated human embryonic stem cells (hESC) into […]
Saturday, January 14, 2012
Retinal Development Kwan KM, Otsuna H, Kidokoro H, Carney KR, Saijoh Y, Chien CB. A complex choreography of cell movements shapes the vertebrate eye. Development. 2012 Jan;139(2):359-72. PubMed PMID: 22186726. Morgan JL, Soto F, Wong RO, Kerschensteiner D. Development of cell type-specific connectivity patterns of converging excitatory axons in the retina. Neuron. 2011 Sep 22;71(6):1014-21. […]
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Also tagged education, evolution, genetics, genomics, medical research, neuroscience, retinal development, systems biology, vision, zebrafish
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Friday, November 25, 2011
From Discover magazine: “Helpful Mouse Fetuses Naturally Send Stem Cells to Mom to Fix Her Damaged Heart” The punchline is When a pregnant mouse has a heart attack, her fetus donates some of its stem cells to help rebuild the damaged heart tissue. The original article is available here. Kara RJ, Bolli P, Karakikes I, […]
We have briefly touched the subject of stem cell research in the last journal club. The challenge of developing “stem cell” as a useful therapy is three fold: Turning the clock of a differentiated cell back to the very beginning. Guiding the resulting dedifferentiated “stem cells” or any kinds of “stem cells” to develop into […]