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Leung Lab presented at the 132nd Annual Academy Meeting of the Indiana Academy of Science

Sunday, April 9, 2017

On 2016-03-25, Khaled Noui-Mehidi presented his research at the 131st Annual Academy Meeting of the Indiana Academy of Science. Emre Coskun attended the meeting. They were supervised by graduate student Logan Ganzen.

Khaled Noui-Mehidi presenting his research at the IAS meeting.

 

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2017-03-20 new articles we read this week

Monday, March 20, 2017

Neuroscience

  1. Dresler M, Shirer WR, Konrad BN, Müller NC, Wagner IC, Fernández G, Czisch M, Greicius MD. Mnemonic Training Reshapes Brain Networks to Support Superior Memory. Neuron. 2017 Mar 8;93(5):1227-1235.e6. doi: 10.1016/j.neuron.2017.02.003. PubMed PMID: 28279356.
  2. Burton CE, Zhou Y, Bai Q, Burton EA. Spectral properties of the zebrafish visual motor response. Neurosci Lett. 2017 Mar 3. pii: S0304-3940(17)30204-5. doi: 10.1016/j.neulet.2017.03.002. [Epub ahead of print] PubMed PMID: 28267562.

Genome editing

  1. Tang L, Zeng Y, Du H, Gong M, Peng J, Zhang B, Lei M, Zhao F, Wang W, Li X, Liu J. CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein. Mol Genet Genomics. 2017 Mar 1. doi: 10.1007/s00438-017-1299-z. [Epub ahead of print] PubMed PMID: 28251317.
  2. Hohmann S. Editor’s comment on “CRISPR/Cas9-mediated gene editing in human zygotes using Cas9 protein”. Mol Genet Genomics. 2017 Mar 1. doi: 10.1007/s00438-017-1300-x. [Epub ahead of print] PubMed PMID: 28251316.

ELSI

  1. Williams WM, Ceci SJ. National hiring experiments reveal 2:1 faculty preference for women on STEM tenure track. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5360-5. doi: 10.1073/pnas.1418878112. PubMed PMID: 25870272; PubMed Central PMCID: PMC4418903.
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2017-03-15 new articles we read this week

Wednesday, March 15, 2017

Genome editing

  1. Why the CRISPR patent verdict isn’t the end of the story
  2. Burstein D, Harrington LB, Strutt SC, Probst AJ, Anantharaman K, Thomas BC, Doudna JA, Banfield JF. New CRISPR-Cas systems from uncultivated microbes. Nature. 2017 Feb 9;542(7640):237-241. doi: 10.1038/nature21059. PubMed PMID: 28005056; PubMed Central PMCID: PMC5300952.

Imaging

  1. Pan C, Cai R, Quacquarelli FP, Ghasemigharagoz A, Lourbopoulos A, Matryba P, Plesnila N, Dichgans M, Hellal F, Ertürk A. Shrinkage-mediated imaging of entire organs and organisms using uDISCO. Nat Methods. 2016 Oct;13(10):859-67. doi: 10.1038/nmeth.3964. PubMed PMID: 27548807.

Neuroscience

  1. Krakauer JW, Ghazanfar AA, Gomez-Marin A, MacIver MA, Poeppel D. Neuroscience Needs Behavior: Correcting a Reductionist Bias. Neuron. 2017 Feb 8;93(3):480-490. doi: 10.1016/j.neuron.2016.12.041. Review. PubMed PMID: 28182904.
  2. Jonas E, Kording KP. Could a Neuroscientist Understand a Microprocessor? PLoS Comput Biol. 2017 Jan 12;13(1):e1005268. doi: 10.1371/journal.pcbi.1005268. PubMed PMID: 28081141; PubMed Central PMCID: PMC5230747.

Medicine

  1. Dowdy SF. Overcoming cellular barriers for RNA therapeutics. Nat Biotechnol. 2017 Feb 27. doi: 10.1038/nbt.3802. [Epub ahead of print] PubMed PMID: 28244992.
  2. Khvorova A, Watts JK. The chemical evolution of oligonucleotide therapies of clinical utility. Nat Biotechnol. 2017 Feb 27. doi: 10.1038/nbt.3765. [Epub ahead of print] PubMed PMID: 28244990.

Genomics

  1. Martelotto LG, Baslan T, Kendall J, Geyer FC, Burke KA, Spraggon L, Piscuoglio S, Chadalavada K, Nanjangud G, Ng CK, Moody P, D’Italia S, Rodgers L, Cox H, da Cruz Paula A, Stepansky A, Schizas M, Wen HY, King TA, Norton L, Weigelt B, Hicks JB, Reis-Filho JS. Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples. Nat Med. 2017 Feb 6. doi: 10.1038/nm.4279. [Epub ahead of print] PubMed PMID: 28165479.

Genetics

  1. Bilow M, Crespo F, Pan Z, Eskin E, Eyheramendy S. Simultaneous Modeling of Disease Status and Clinical Phenotypes to Increase Power in GWAS. Genetics. 2017 Jan 27. pii: genetics.116.198473. doi: 10.1534/genetics.116.198473. [Epub ahead of print] PubMed PMID: 28132020.


				

				

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2017-02-20 new articles we read this week

				
Monday, February 20, 2017

				


Genome editing


    

  1. Park RJ, Wang T, Koundakjian D, Hultquist JF, Lamothe-Molina P, Monel B, Schumann K, Yu H, Krupzcak KM, Garcia-Beltran W, Piechocka-Trocha A, Krogan NJ, Marson A, Sabatini DM, Lander ES, Hacohen N, Walker BD. A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors. Nat Genet. 2017 Feb;49(2):193-203. doi: 10.1038/ng.3741. PubMed PMID: 27992415.

      

    • Commentary: Tsui CK, Gupta A, Bassik MC. Finding host targets for HIV therapy. Nat Genet. 2017 Jan 31;49(2):175-176. doi: 10.1038/ng.3777. PubMed PMID: 28138150.
      • 

    

    2. 

  2. Bengtsson NE, Hall JK, Odom GL, Phelps MP, Andrus CR, Hawkins RD, Hauschka SD, Chamberlain JR, Chamberlain JS. Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy. Nat Commun. 2017 Feb 14;8:14454. doi: 10.1038/ncomms14454. PubMed PMID: 28195574.
    3. 



Disease


    

  1. Leinenga G, Götz J. Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer’s disease mouse model. Sci Transl Med. 2015 Mar 11;7(278):278ra33. doi: 10.1126/scitranslmed.aaa2512. PubMed PMID: 25761889.


    2. 



				

				

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2017-01-30 new articles we read this week

				
Monday, January 30, 2017

				


Genomics


    

  1. Li X, Xiong X, Yi C. Epitranscriptome sequencing technologies: decoding RNA modifications. Nat Methods. 2016 Dec 29;14(1):23-31. doi: 10.1038/nmeth.4110. PubMed PMID: 28032622.
    2. 

  2. Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. PubMed PMID: 27984733.
    3. 

  3. Dixit A, Parnas O, Li B, Chen J, Fulco CP, Jerby-Arnon L, Marjanovic ND, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman TM, Lander ES, Weissman JS, Friedman N, Regev A. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016 Dec 15;167(7):1853-1866.e17. doi: 10.1016/j.cell.2016.11.038. PubMed PMID: 27984732; PubMed Central PMCID: PMC5181115.
    4. 

  4. Jaitin DA, Weiner A, Yofe I, Lara-Astiaso D, Keren-Shaul H, David E, Salame TM, Tanay A, van Oudenaarden A, Amit I. Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq. Cell. 2016 Dec 15;167(7):1883-1896.e15. doi: 10.1016/j.cell.2016.11.039. PubMed PMID: 27984734.
    5. 



RNA 


    

  1. Rivas E, Clements J, Eddy SR. A statistical test for conserved RNA structure shows lack of evidence for structure in lncRNAs. Nat Methods. 2017 Jan;14(1):45-48. doi: 10.1038/nmeth.4066. PubMed PMID: 27819659.
    2. 



 Cell cycle


    

  1. Swaffer MP, Jones AW, Flynn HR, Snijders AP, Nurse P. CDK Substrate Phosphorylation and Ordering the Cell Cycle. Cell. 2016 Dec 15;167(7):1750-1761.e16. doi: 10.1016/j.cell.2016.11.034. PubMed PMID: 27984725; PubMed Central PMCID: PMC5161751.
    2. 



Genome Editing


    

  1. Pawluk A, Amrani N, Zhang Y, Garcia B, Hidalgo-Reyes Y, Lee J, Edraki A, Shah M, Sontheimer EJ, Maxwell KL, Davidson AR. Naturally Occurring Off-Switches for CRISPR-Cas9. Cell. 2016 Dec 15;167(7):1829-1838.e9. doi: 10.1016/j.cell.2016.11.017. PubMed PMID: 27984730.
    2. 

  2. Adamson B, Norman TM, Jost M, Cho MY, Nuñez JK, Chen Y, Villalta JE, Gilbert LA, Horlbeck MA, Hein MY, Pak RA, Gray AN, Gross CA, Dixit A, Parnas O, Regev A, Weissman JS. A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response. Cell. 2016 Dec 15;167(7):1867-1882.e21. doi: 10.1016/j.cell.2016.11.048. PubMed PMID: 27984733.
    3. 

  3. Dixit A, Parnas O, Li B, Chen J, Fulco CP, Jerby-Arnon L, Marjanovic ND, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman TM, Lander ES, Weissman JS, Friedman N, Regev A. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016 Dec 15;167(7):1853-1866.e17. doi: 10.1016/j.cell.2016.11.038. PubMed PMID: 27984732; PubMed Central PMCID: PMC5181115.
    4. 

  4. Jaitin DA, Weiner A, Yofe I, Lara-Astiaso D, Keren-Shaul H, David E, Salame TM, Tanay A, van Oudenaarden A, Amit I. Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq. Cell. 2016 Dec 15;167(7):1883-1896.e15. doi: 10.1016/j.cell.2016.11.039. PubMed PMID: 27984734.
    5. 

  5. Sheridan C. CRISPR therapeutics push into human testing. Nat Biotechnol. 2017 Jan 10;35(1):3-5. doi: 10.1038/nbt0117-3. PubMed PMID: 28072788.
    6. 



Zebrafish


    

  1. Reade A, Motta-Mena LB, Gardner KH, Stainier DY, Weiner OD, Woo S. TAEL: A zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control. Development. 2016 Dec 19. pii: dev.139238. [Epub ahead of print] PubMed PMID: 27993986.
    2. 



Stem Cells


    

  1. Mandai M, Fujii M, Hashiguchi T, Sunagawa GA, Ito S, Sun J, Kaneko J, Sho J, Yamada C, Takahashi M. iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration Mice. Stem Cell Reports. 2017 Jan 10;8(1):69-83. doi: 10.1016/j.stemcr.2016.12.008. PubMed PMID: 28076757.
    2. 





				

				

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2017-01-17 new articles we read this week

				
Tuesday, January 17, 2017

				


Evolution


    

  1. Gonzalez P, Uhlinger KR, Lowe CJ. The Adult Body Plan of Indirect Developing Hemichordates Develops by Adding a Hox-Patterned Trunk to an Anterior Larval Territory. Curr Biol. 2016 Dec 7. pii: S0960-9822(16)31273-8. doi: 10.1016/j.cub.2016.10.047. [Epub ahead of print] PubMed PMID: 27939313.

      

    • Hejnol A, Vellutini BC. Larval Evolution: I’ll Tail You Later…. Curr Biol. 2017 Jan 9;27(1):R21-R24. doi: 10.1016/j.cub.2016.10.057. PubMed PMID: 28073016.
      • 

    

    2. 



Regeneration


    

  1. Tornini VA, Puliafito A, Slota LA, Thompson JD, Nachtrab G, Kaushik AL, Kapsimali M, Primo L, Di Talia S, Poss KD. Live Monitoring of Blastemal Cell Contributions during Appendage Regeneration. Curr Biol. 2016 Nov 21;26(22):2981-2991. doi: 10.1016/j.cub.2016.08.072. PubMed PMID: 27839971; PubMed Central PMCID: PMC5121098.
    2. 

  2. Currie JD, Kawaguchi A, Traspas RM, Schuez M, Chara O, Tanaka EM. Live Imaging of Axolotl Digit Regeneration Reveals Spatiotemporal Choreography of Diverse Connective Tissue Progenitor Pools. Dev Cell. 2016 Nov 21;39(4):411-423. doi: 10.1016/j.devcel.2016.10.013. PubMed PMID: 27840105; PubMed Central PMCID: PMC5127896.

      

    • Weidinger G. Regeneration: Recorded Live! Curr Biol. 2017 Jan 9;27(1):R30-R33. doi: 10.1016/j.cub.2016.11.022. PubMed PMID: 28073020.
      • 

    

    3. 



				

				

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2017-01-10 new articles we read this week

				
Tuesday, January 10, 2017

				


Behaviour


    

  1. Dreosti E, Lopes G, Kampff AR, Wilson SW. Development of social behavior in young zebrafish. Front Neural Circuits. 2015 Aug 18;9:39. doi: 10.3389/fncir.2015.00039. eCollection 2015. PubMed PMID: 26347614; PubMed Central PMCID: PMC4539524.
    2. 

  2. Pérez-Escudero A, Vicente-Page J, Hinz RC, Arganda S, de Polavieja GG. idTracker: tracking individuals in a group by automatic identification of unmarked animals. Nat Methods. 2014 Jul;11(7):743-8. doi: 10.1038/nmeth.2994. Epub 2014 Jun 1. PubMed PMID: 24880877.
    3. 



Genome editing


    

  1. Kuscu C, Adli M. CRISPR-Cas9-AID base editor is a powerful gain-of-function screening tool. Nat Methods. 2016 Nov 29;13(12):983-984. doi: 10.1038/nmeth.4076. PubMed PMID: 27898061. Ma Y, Zhang J, Yin W, Zhang Z, Song Y, Chang X. Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells. Nat Methods. 2016 Dec;13(12):1029-1035. doi: 10.1038/nmeth.4027. PubMed PMID: 27723754.
    2. 

  2. Hess GT, Frésard L, Han K, Lee CH, Li A, Cimprich KA, Montgomery SB, Bassik MC. Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. Nat Methods. 2016 Dec;13(12):1036-1042. doi: 10.1038/nmeth.4038. PubMed PMID: 27798611. Gao Y, Xiong X, Wong S, Charles EJ, Lim WA, Qi LS. Complex transcriptional modulation with orthogonal and inducible dCas9 regulators. Nat Methods. 2016 Dec;13(12):1043-1049. doi: 10.1038/nmeth.4042. PubMed PMID: 27776111.
    3. 

  3. Nakamura T, Gehrke AR, Lemberg J, Szymaszek J, Shubin NH. Digits and fin rays share common developmental histories. Nature. 2016 Sep 8;537(7619):225-228. doi: 10.1038/nature19322. PubMed PMID: 27533041; PubMed Central PMCID: PMC5161576.

      

    • CRISPR helps evo-devo scientists to unpick the origins of adaptions. Nature. 2016 Aug 18;536(7616):249. doi: 10.1038/536249b. PubMed PMID: 27535498.
      • 

    • Saxena A, Cooper KL. Evolutionary biology: Fin to limb within our grasp. Nature. 2016 Sep 8;537(7619):176-177. doi: 10.1038/nature19425. PubMed PMID: 27533039.
      • 

    

    4. 



Genetics/Genomics


    

  1. Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, O’Donnell-Luria AH, Ware JS, Hill AJ, Cummings BB, Tukiainen T, Birnbaum DP, Kosmicki JA, Duncan LE, Estrada K, Zhao F, Zou J, Pierce-Hoffman E, Berghout J, Cooper DN, Deflaux N, DePristo M, Do R, Flannick J, Fromer M, Gauthier L, Goldstein J, Gupta N, Howrigan D, Kiezun A, Kurki MI, Moonshine AL, Natarajan P, Orozco L, Peloso GM, Poplin R, Rivas MA, Ruano-Rubio V, Rose SA, Ruderfer DM, Shakir K, Stenson PD, Stevens C, Thomas BP, Tiao G, Tusie-Luna MT, Weisburd B, Won HH, Yu D, Altshuler DM, Ardissino D, Boehnke M, Danesh J, Donnelly S, Elosua R, Florez JC, Gabriel SB, Getz G, Glatt SJ, Hultman CM, Kathiresan S, Laakso M, McCarroll S, McCarthy MI, McGovern D, McPherson R, Neale BM, Palotie A, Purcell SM, Saleheen D, Scharf JM, Sklar P, Sullivan PF, Tuomilehto J, Tsuang MT, Watkins HC, Wilson JG, Daly MJ, MacArthur DG; Exome Aggregation Consortium.. Analysis of protein-coding genetic variation in 60,706 humans. Nature. 2016 Aug 18;536(7616):285-91. doi: 10.1038/nature19057. PubMed PMID: 27535533; PubMed Central PMCID: PMC5018207.
    2. 

  2. Shendure J. Human genomics: A deep dive into genetic variation. Nature. 2016 Aug 18;536(7616):277-8. doi: 10.1038/536277a. PubMed PMID: 27535530.
    3. 

  3. ExAC project pins down rare gene variants. Nature. 2016 Aug 18;536(7616):249. doi: 10.1038/536249a. PubMed PMID: 27535499.
    4. 

  4. Carss KJ, Arno G, Erwood M, Stephens J, Sanchis-Juan A, Hull S, Megy K, Grozeva D, Dewhurst E, Malka S, Plagnol V, Penkett C, Stirrups K, Rizzo R, Wright G, Josifova D, Bitner-Glindzicz M, Scott RH, Clement E, Allen L, Armstrong R, Brady AF, Carmichael J, Chitre M, Henderson RH, Hurst J, MacLaren RE, Murphy E, Paterson J, Rosser E, Thompson DA, Wakeling E, Ouwehand WH, Michaelides M, Moore AT; NIHR-BioResource Rare Diseases Consortium., Webster AR, Raymond FL. Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease. Am J Hum Genet. 2016 Dec 28. pii: S0002-9297(16)30527-4. doi: 10.1016/j.ajhg.2016.12.003. [Epub ahead of print] PubMed PMID: 28041643.
    5. 



Evolution


    

  1. Nakamura T, Gehrke AR, Lemberg J, Szymaszek J, Shubin NH. Digits and fin rays share common developmental histories. Nature. 2016 Sep 8;537(7619):225-228. doi: 10.1038/nature19322. PubMed PMID: 27533041; PubMed Central PMCID: PMC5161576.
    2. 

  2. CRISPR helps evo-devo scientists to unpick the origins of adaptions. Nature. 2016 Aug 18;536(7616):249. doi: 10.1038/536249b. PubMed PMID: 27535498.
    3. 

  3. Saxena A, Cooper KL. Evolutionary biology: Fin to limb within our grasp. Nature. 2016 Sep 8;537(7619):176-177. doi: 10.1038/nature19425. PubMed PMID: 27533039.
    4. 



System biology


    

  1. Gao Y, Xiong X, Wong S, Charles EJ, Lim WA, Qi LS. Complex transcriptional modulation with orthogonal and inducible dCas9 regulators. Nat Methods. 2016 Dec;13(12):1043-1049. doi: 10.1038/nmeth.4042. PubMed PMID: 27776111.
    2. 

  2. Frumkin I, Schirman D, Rotman A, Li F, Zahavi L, Mordret E, Asraf O, Wu S, Levy SF, Pilpel Y. Gene Architectures that Minimize Cost of Gene Expression. Mol Cell. 2016 Nov 25. pii: S1097-2765(16)30715-8. doi: 10.1016/j.molcel.2016.11.007. [Epub ahead of print] PubMed PMID: 27989436.
    3. 







				

				

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2016-08-10 new articles we read this week

				
Wednesday, August 10, 2016

				


Genome editing


    

  1. Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT. Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. Proc Natl Acad Sci U S A. 2016 Jun 20. pii: 201600582. [Epub ahead of print] PubMed PMID: 27325776.
    2. 



Regeneration


    

  1. Neves J, Zhu J, Sousa-Victor P, Konjikusic M, Riley R, Chew S, Qi Y, Jasper H, Lamba DA. Immune modulation by MANF promotes tissue repair and regenerative success in the retina. Science. 2016 Jul 1;353(6294):aaf3646. doi: 10.1126/science.aaf3646. PubMed PMID: 27365452.
    2. 



Genomics


    

  1. Ståhl PL, Salmén F, Vickovic S, Lundmark A, Navarro JF, Magnusson J, Giacomello S, Asp M, Westholm JO, Huss M, Mollbrink A, Linnarsson S, Codeluppi S, Borg Å, Pontén F, Costea PI, Sahlén P, Mulder J, Bergmann O, Lundeberg J, Frisén J. Visualization and analysis of gene expression in tissue sections by spatial transcriptomics. Science. 2016 Jul 1;353(6294):78-82. doi: 10.1126/science.aaf2403. PubMed PMID: 27365449.
    2. 

  2. Wu J, Huang B, Chen H, Yin Q, Liu Y, Xiang Y, Zhang B, Liu B, Wang Q, Xia W, Li W, Li Y, Ma J, Peng X, Zheng H, Ming J, Zhang W, Zhang J, Tian G, Xu F, Chang Z, Na J, Yang X, Xie W. The landscape of accessible chromatin in mammalian preimplantation embryos. Nature. 2016 Jun 15;534(7609):652-657. doi: 10.1038/nature18606. [Epub ahead of print] PubMed PMID: 27309802.
    3. 



 Development


    

  1. Wu J, Huang B, Chen H, Yin Q, Liu Y, Xiang Y, Zhang B, Liu B, Wang Q, Xia W, Li W, Li Y, Ma J, Peng X, Zheng H, Ming J, Zhang W, Zhang J, Tian G, Xu F, Chang Z, Na J, Yang X, Xie W. The landscape of accessible chromatin in mammalian preimplantation embryos. Nature. 2016 Jun 15;534(7609):652-657. doi: 10.1038/nature18606. [Epub ahead of print] PubMed PMID: 27309802.
    2. 



Funding


    

  1. von Hippel T, von Hippel C. To apply or not to apply: a survey analysis of grant writing costs and benefits. PLoS One. 2015 Mar 4;10(3):e0118494. doi: 10.1371/journal.pone.0118494. eCollection 2015. PubMed PMID: 25738742; PubMed Central PMCID: PMC4349454.
    2. 





				

				

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My visit to the School of Optometry of the Hong Kong Polytechnic University.

				
Saturday, August 6, 2016

				


On July 20th 2016, I was invited by Dr. Chi-ho To, Professor and Head, and Dr. Chi-wai Do to visit the School of Optometry of the Hong Kong Polytechnic University. This is the leading Optometry school in Hong Kong and Asia. They have also been conducting many research programs that lead to translational products that help eye-disease patients. Their cohesive and collegial team great enhances efficiency and contributes to their success in research. During my visit, I gave a seminar on “Discover New Drugs for Retinal Degeneration by Zebrafish Research” and shared our vision on using this research platform to help patients with this great research team.


Yuk Fai Leung with the Professors from the School of Optometry at the Hong Kong Polytechnic University.


Yuk Fai Leung shared his vision on zebrafish research.


Yuk Fai Leung shared his vision on zebrafish research.


				

				

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My visit to Dr. Zi-Bing Jin’s group at the Eye Hospital of Wenzhou Medical University

				
Saturday, August 6, 2016

				


On July 18th and 19th of 2016, I was invited by Dr. Zi-Bing Jin to visit his research group at the Eye Hospital of Wenzhou Medical University in Wenzhou, China again. They are doing amazing work on various aspects of ophthalmology, from human genetics, stem cells, microRNAs to zebrafish. We have been working together on the zebrafish platform for years, and it is gratifying to see Dr. Jin’s group’s development over the years. When I visited them every time, I was always impressed by how enthusiastic and hard working the Wenzhou students are. Dr. Jin’s group probably has 30 to 40 students. Most of them work at least 12 hours in the lab every day! With this dedication, no wonder many Chinese students are making a big contribution to science these days.


A few pictures of my visit:


Yuk Fai Leung gave a research talk on using zebrafish to discover new drugs for rod degeneration to the students at Wenzhou Medical University.


 


Dr. Zi-Bing Jin at Wenzhou Medical University shared his research vision with Yuk Fai Leung.


Yuk Fai Leung gave a workshop on “Effective Scientific Communication”. In this workshop, I shared with the enthusiastic students many writing tricks and communication skills that I learned through experience over the years. These skills are particularly suitable for those of us who speak English as a second language and want to effectively communicate our findings to the research community.


				

				

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