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2010-12-04 articles we read this week

Saturday, December 4, 2010

Origin of Life

  1. Wolfe-Simon F, Blum JS, Kulp TR, Gordon GW, Hoeft SE, Pett-Ridge J, Stolz JF, Webb SM, Weber PK, Davies PC, Anbar AD, Oremland RS. A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus. Science. 2010 Dec 2. [Epub ahead of print] PubMed PMID: 21127214.
    • News coverage on BBC

Image analysis

  1. Shamir L, Delaney JD, Orlov N, Eckley DM, Goldberg IG. Pattern recognition software and techniques for biological image analysis. PLoS Comput Biol. 2010 Nov 24;6(11):e1000974. PubMed PMID: 21124870.
  2. Wollman R, Stuurman N. High throughput microscopy: from raw images to discoveries. J Cell Sci. 2007 Nov 1;120(Pt 21):3715-22. Review. PubMed PMID: 17959627.
  3. Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, Guertin DA, Chang JH, Lindquist RA, Moffat J, Golland P, Sabatini DM. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol. 2006;7(10):R100. Epub 2006 Oct 31. PubMed PMID: 17076895; PubMed Central PMCID: PMC1794559.
  4. Jones TR, Kang IH, Wheeler DB, Lindquist RA, Papallo A, Sabatini DM, Golland P, Carpenter AE. CellProfiler Analyst: data exploration and analysis software for complex image-based screens. BMC Bioinformatics. 2008 Nov 15;9:482. PubMed PMID: 19014601; PubMed Central PMCID: PMC2614436.
  5. Jones TR, Carpenter AE, Lamprecht MR, Moffat J, Silver SJ, Grenier JK, Castoreno AB, Eggert US, Root DE, Golland P, Sabatini DM. Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1826-31. Epub 2009 Feb 2.  PubMed PMID: 19188593; PubMed Central PMCID: PMC2634799.
  6. Lamprecht MR, Sabatini DM, Carpenter AE. CellProfiler: free, versatile software for automated biological image analysis. Biotechniques. 2007 Jan;42(1):71-5. PubMed PMID: 17269487.

Neuroscience

  1. Schwab ME. How hard is the CNS hardware? Nat Neurosci. 2010 Dec;13(12):1444-6. PubMed PMID: 21102566.

Retina

  1. Fischer AJ, Bongini R. Turning müller glia into neural progenitors in the retina. Mol Neurobiol. 2010 Dec;42(3):199-209. Epub 2010 Nov 20. PubMed PMID:21088932.

Genomics

  1. Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol. 2010 Oct 27;11(10):R106. [Epub ahead of print] PubMed PMID: 20979621.
  2. Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci U S A. 2010 Nov 24. [Epub ahead of print] PubMed PMID: 21106759.

Brg1

  1. Watanabe T, Semba S, Yokozaki H. Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells. Br J Cancer. 2010 Nov 23. [Epub ahead of print] PubMed PMID: 21102582.

Physiology

  1. Ng SF, Lin RC, Laybutt DR, Barres R, Owens JA, Morris MJ. Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring. Nature. 2010 Oct 21;467(7318):963-6. PubMed PMID: 20962845.

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2010-11-27 New articles we read this week

Saturday, November 27, 2010

Zebrafish

  1. Knopf F, Schnabel K, Haase C, Pfeifer K, Anastassiadis K, Weidinger G. Dually inducible TetON systems for tissue-specific conditional gene expression in zebrafish. Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19933-19938. Epub 2010 Nov 1. PubMed PMID: 21041642.
  2. Connaughton VP. Bipolar cells in the zebrafish retina. Vis Neurosci. 2010 Nov 16:1-17. [Epub ahead of print] PubMed PMID: 21080977.
  3. Arrenberg AB, Stainier DY, Baier H, Huisken J. Optogenetic control of cardiac function. Science. 2010 Nov 12;330(6006):971-4. PubMed PMID: 21071670.

Neuroscience

  1. Yehuda R, Joëls M, Morris RG. The memory paradox. Nat Rev Neurosci. 2010 Dec;11(12):837-839. PubMed PMID: 21088685.
  2. Del Bene F, Wyart C, Robles E, Tran A, Looger L, Scott EK, Isacoff EY, Baier H. Filtering of visual information in the tectum by an identified neural circuit. Science. 2010 Oct 29;330(6004):669-73. PubMed PMID: 21030657.

Medicine

  1. D’Amato G, Liccardi G, Cecchi L, Pellegrino F, D’Amato M. Facebook: a new trigger for asthma? Lancet. 2010 Nov 20;376(9754):1740. PubMed PMID: 21093651.

Eye & Disease

  1. Parapuram SK, Cojocaru RI, Chang JR, Khanna R, Brooks M, Othman M, Zareparsi S, Khan NW, Gotoh N, Cogliati T, Swaroop A. Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases. PLoS One. 2010 Nov 8;5(11):e13885. PubMed PMID: 21079736; PubMed Central PMCID: PMC2975639.
  2. Connaughton VP. Bipolar cells in the zebrafish retina. Vis Neurosci. 2010 Nov 16:1-17. [Epub ahead of print] PubMed PMID: 21080977.
  3. Tschopp M, Takamiya M, Cerveny KL, Gestri G, Biehlmaier O, Wilson SW, Strähle U, Neuhauss SC. Funduscopy in adult zebrafish and its application to isolate mutant strains with ocular defects. PLoS One. 2010 Nov 5;5(11):e15427. PubMed PMID: 21079775; PubMed Central PMCID: PMC2974646.
  4. den Hollander AI, Biyanwila J, Kovach P, Bardakjian T, Traboulsi EI, Ragge NK, Schneider A, Malicki J. Genetic defects of GDF6 in the zebrafish out of sightmutant and in human eye developmental anomalies. BMC Genet. 2010 Nov 11;11(1):102. PubMed PMID: 21070663.
  5. Maminishkis A, Miller SS. Experimental models for study of retinal pigment epithelial physiology and pathophysiology. J Vis Exp. 2010 Nov 6;(45). pii: 2032. doi: 10.3791/2032. PubMed PMID: 21085105.

Systems biology

  1. Larsson E, Sander C, Marks D. mRNA turnover rate limits siRNA and microRNA efficacy. Mol Syst Biol. 2010 Nov 16;6:433. PubMed PMID: 21081925.
  2. Mao C, Brown CR, Falkovskaia E, Dong S, Hrabeta-Robinson E, Wenger L, Boeger H. Quantitative analysis of the transcription control mechanism. Mol Syst Biol. 2010 Nov 19;6:431. PubMed PMID: 21081924.

Funding

  1. Gross M. Britain cuts back deeply on spending. Curr Biol. 2010 Nov 9;20(21):R905-6. PubMed PMID: 21105219.
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Conrad Wolfram: Teaching kids real math with computers

Sunday, November 21, 2010

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2010-11-20 New articles we read this week

Saturday, November 20, 2010

Disease

  1. Shive HR, West RR, Embree LJ, Azuma M, Sood R, Liu P, Hickstein DD. brca2 in zebrafish ovarian development, spermatogenesis, and tumorigenesis. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19350-5. Epub 2010 Oct 25. PubMed PMID: 20974951.
  2. Jain S, Heutink P. From single genes to gene networks: high-throughput-high-content screening for neurological disease. Neuron. 2010 Oct 21;68(2):207-17. Review. PubMed PMID: 20955929.

Eye Disease

  1. Linder B, Dill H, Hirmer A, Brocher J, Lee GP, Mathavan S, Bolz HJ, Winkler C, Laggerbauer B, Fischer U. Systemic splicing factor deficiency causes tissue-specific defects: A zebrafish model for Retinitis pigmentosa. Hum Mol Genet. 2010 Nov 3. [Epub ahead of print] PubMed PMID: 21051334.

Development

  1. Lek M, Dias JM, Marklund U, Uhde CW, Kurdija S, Lei Q, Sussel L, Rubenstein JL, Matise MP, Arnold HH, Jessell TM, Ericson J. A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning. Development. 2010 Dec;137(23):4051-60. PubMed PMID: 21062862.
  2. Green AA, Kennaway JR, Hanna AI, Bangham JA, Coen E. Genetic Control of Organ Shape and Tissue Polarity. PLoS Biol. 2010 Nov 9;8(11):e1000537. PubMed PMID: 21085690.
  3. Cui ML, Copsey L, Green AA, Bangham JA, Coen E. Quantitative Control of Organ Shape by Combinatorial Gene Activity. PLoS Biol. 2010 Nov 9;8(11):e1000538. PubMed PMID: 21085695.

Eye Development

  1. Billings NA, Emerson MM, Cepko CL. Analysis of Thyroid Response Element Activity during Retinal Development. PLoS One. 2010 Oct 29;5(10):e13739. PubMed PMID: 21060789; PubMed Central PMCID: PMC2966421.
  2. Phillips MJ, Otteson DC. Differential expression of neuronal genes in Muller glia in two- and three-dimensional cultures. Invest Ophthalmol Vis Sci. 2010 Nov 4. [Epub ahead of print] PubMed PMID: 21051699.

Stem Cells

  1. Hanna JH, Saha K, Jaenisch R. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell. 2010 Nov 12;143(4):508-25. PubMed PMID: 21074044.
  2. Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR. A model for neural development and treatment of rett syndrome using humaninduced pluripotent stem cells. Cell. 2010 Nov 12;143(4):527-39. PubMed PMID: 21074045.

Zebrafish

  1. Newman M, Lardelli M. A hyperactive sleeping beauty transposase enhances transgenesis in zebrafish embryos. BMC Res Notes. 2010 Nov 4;3(1):282. [Epub ahead of print] PubMed PMID: 21050486.

Genomics

  1. Wyart M, Botstein D, Wingreen NS. Evaluating Gene Expression Dynamics Using Pairwise RNA FISH Data. PLoS Comput Biol. 2010 Nov 4;6(11):e1000979. PubMed PMID: 21079668; PubMed Central PMCID: PMC2973809.

Systems Biology

  1. Lehner B. Conflict between Noise and Plasticity in Yeast. PLoS Genet. 2010 Nov 4;6(11):e1001185. PubMed PMID: 21079670; PubMed Central PMCID: PMC2973811.
  2. Li J, Yuan Z, Zhang Z. The cellular robustness by genetic redundancy in budding yeast. PLoS Genet. 2010 Nov 4;6(11):e1001187. PubMed PMID: 21079672; PubMed Central PMCID: PMC2973813.

Ethics, Society and Legal Issues

  1. Johnson DG. The role of ethics in science and engineering. Trends Biotechnol. 2010 Sep 9. [Epub ahead of print] PubMed PMID: 20832883.
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Interesting article on the evolution of the heart.

Thursday, November 18, 2010

Reptilian heart development and the molecular basis of cardiac chamber evolution. Nature 461, 95-98 (3 September 2009). It also has some really nice photos. Enjoy!

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RSA Animate – Drive: The surprising truth about what motivates us

Sunday, November 14, 2010

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2010-11-13 Articles we read this week

Saturday, November 13, 2010

Retina & regeneration

  1. Corbo JC, Lawrence KA, Karlstetter M, Myers CA, Abdelaziz M, Dirkes W, Weigelt K, Seifert M, Benes V, Fritsche LG, Weber BH, Langmann T. CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors. Genome Res. 2010 Nov;20(11):1512-25. Epub 2010 Aug 6. PubMed PMID: 20693478.
  2. Ramachandran R, Fausett BV, Goldman D. Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway. Nat Cell Biol. 2010 Nov;12(11):1101-7. Epub 2010 Oct 10. PubMed PMID: 20935637; PubMed Central PMCID: PMC2972404.
  3. Choy SW, Cheng CW, Lee ST, Li VW, Hui MN, Hui CC, Liu D, Cheng SH.  A cascade of irx1a and irx2a controls shh expression during retinogenesis. Dev Dyn. 2010 Nov 2;. [Epub ahead of print]
  4. Choi JH, Law MY, Chien CB, Link BA, Wong RO. In vivo development of dendritic orientation in wild-type and mislocalized retinal ganglion cells. Neural Dev. 2010 Nov 2;5(1):29. [Epub ahead of print] PubMed PMID: 21044295.

Development

  1. Apodaca G. Opening ahead: early steps in lumen formation revealed. Nat Cell Biol. 2010 Nov;12(11):1026-8. PubMed PMID: 21045801.
  2. Morris JA, Royall JJ, Bertagnolli D, Boe AF, Burnell JJ, Byrnes EJ, Copeland C, Desta T, Fischer SR, Goldy J, Glattfelder KJ, Kidney JM, Lemon T, Orta GJ, Parry SE, Pathak SD, Pearson OC, Reding M, Shapouri S, Smith KA, Soden C, Solan BM, Weller J, Takahashi JS, Overly CC, Lein ES, Hawrylycz MJ, Hohmann JG, Jones AR. Divergent and nonuniform gene expression patterns in mouse brain. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19049-54. Epub 2010 Oct 18. PubMed PMID: 20956311.
  3. Pedersen MT, Helin K. Histone demethylases in development and disease. Trends  Cell Biol. 2010 Nov;20(11):662-71. Epub 2010 Sep 20. PubMed PMID: 20863703.

Gene regulatory network & Systems biology

  1. Cotterell J, Sharpe J. An atlas of gene regulatory networks reveals multiple three-gene mechanisms for interpreting morphogen gradients. Mol Syst Biol. 2010 Nov 2;6:425. PubMed PMID: 21045819.
  2. Salazar C, Brümmer A, Alberghina L, Höfer T. Timing control in regulatory networks by multisite protein modifications. Trends Cell Biol. 2010 Nov;20(11):634-41. Epub 2010 Sep 23. PubMed PMID: 20869247.

Disease

  1. Van Broeckhoven C. The future of genetic research on neurodegeneration. Nat Med. 2010 Nov;16(11):1215-7. Epub 2010 Sep 21. PubMed PMID: 21052076.
  2. Jucker M. The benefits and limitations of animal models for translational research in neurodegenerative diseases. Nat Med. 2010 Nov;16(11):1210-4. Epub 2010 Sep 21. PubMed PMID: 21052075.
  3. Haass C. Initiation and propagation of neurodegeneration. Nat Med. 2010 Nov;16(11):1201-4. Epub 2010 Sep 21. PubMed PMID: 21052073.
  4. Jacobson SG, Cideciyan AV. Treatment possibilities for retinitis pigmentosa. N Engl J Med. 2010 Oct 21;363(17):1669-71. PubMed PMID: 20961252.
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2010-11-06 Articles we read this week

Saturday, November 6, 2010

Immunity

  1. Mallery DL, McEwan WA, Bidgood SR, Towers GJ, Johnson CM, James LC. Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21). Proc Natl Acad Sci U S A. 2010 Nov 2. [Epub ahead of print] PubMed PMID: 21045130.

Medicine

  1. Zrenner E, Bartz-Schmidt KU, Benav H, Besch D, Bruckmann A, Gabel VP, Gekeler F, Greppmaier U, Harscher A, Kibbel S, Koch J, Kusnyerik A, Peters T, Stingl K, Sachs H, Stett A, Szurman P, Wilhelm B, Wilke R. Subretinal electronic chips allow blind patients to read letters and combine them to words. Proc Biol Sci. 2010 Nov 3. [Epub ahead of print] PubMed PMID: 21047851.]

Gene regulatory network

  1. Kuo D, Licon K, Bandyopadhyay S, Chuang R, Luo C, Catalana J, Ravasi T, Tan K, Ideker T.   Coevolution within a transcriptional network by compensatory trans and cis mutations. Genome Res. 2010 Oct 26;. [Epub ahead of print]

Genomics

  1. Human genome: Genomes by the thousand. Nature. 2010 Oct 28;467(7319):1026-7. PubMed PMID: 20981067.
  2. Nielsen R. Genomics: In search of rare human variants. Nature. 2010 Oct 28;467(7319):1050-1. PubMed PMID: 20981085.
  3. Luebeck EG. Cancer: Genomic evolution of metastasis. Nature. 2010 Oct 28;467(7319):1053-5. PubMed PMID: 20981088.
  4. 1000 Genomes Project Consortium, Durbin RM, Abecasis GR, Altshuler DL, Auton A, Brooks LD, Durbin RM, Gibbs RA, Hurles ME, McVean GA. A map of human genome variation from population-scale sequencing. Nature. 2010 Oct 28;467(7319):1061-73. PubMed PMID: 20981092.
  5. Lane N, Martin W. The energetics of genome complexity. Nature. 2010 Oct 21;467(7318):929-34. PubMed PMID: 20962839.

Development

  1. Varner VD, Voronov DA, Taber LA. Mechanics of head fold formation: investigating tissue-level forces during early development. Development. 2010 Nov;137(22):3801-11. Epub 2010 Oct 7. PubMed PMID: 20929950.

Retina

  1. Curcio CA, Sloan KR, Kalina RE, Hendrickson AE. Human photoreceptor topography. J Comp Neurol. 1990 Feb 22;292(4):497-523. PubMed PMID: 2324310.

Behaviour

  1. Cachat J, Stewart A, Grossman L, Gaikwad S, Kadri F, Chung KM, Wu N, Wong K, Roy S, Suciu C, Goodspeed J, Elegante M, Bartels B, Elkhayat S, Tien D, Tan J, Denmark A, Gilder T, Kyzar E, Dileo J, Frank K, Chang K, Utterback E, Hart P, Kalueff AV. Measuring behavioral and endocrine responses to novelty stress in adult zebrafish. Nat Protoc. 2010 Oct;5(11):1786-99. Epub 2010 Oct 14. PubMed PMID: 21030954.

Neuroscience

  1. Pyc MA, Rawson KA. Why testing improves memory: mediator effectiveness hypothesis. Science. 2010 Oct 15;330(6002):335. PubMed PMID: 20947756.

Imaging

  1. Ariga J, Walker SL, Mumm JS. Multicolor Time-lapse Imaging of Transgenic Zebrafish: Visualizing Retinal Stem Cells Activated by Targeted Neuronal Cell Ablation. J Vis Exp. 2010 Sep 20;(43). pii: 2093. doi: 10.3791/2093. PubMed PMID: 20972390.

Stem cells

  1. Pera MF. Defining pluripotency. Nat Methods. 2010 Nov;7(11):885-7. PubMed PMID: 21030963.
  2. Verzi MP, Shivdasani RA. Stem cells: The intestinal-crypt casino. Nature. 2010 Oct 28;467(7319):1055-6. PubMed PMID: 20981089.

Chromatin remodeling

  1. Saladi SV, Keenen B, Marathe HG, Qi H, Chin KV, de la Serna IL. Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness. Mol Cancer. 2010 Oct 22;9(1):280. [Epub ahead of print] PubMed PMID: 20969766.

Cdk5

  1. He L, Zhang Z, Yu Y, Ahmed S, Cheung NS, Qi RZ. The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein. Cell Mol Life Sci. 2010 Oct 26. [Epub ahead of print] PubMed PMID: 20976519.

Ethics, Society and Legal Issues

  1. Udesky L. The ethics of direct-to-consumer genetic testing. Lancet. 2010 Oct 23;376(9750):1377-8. PubMed PMID: 20979325.
  2. Macilwain C. Scientists vs engineers: this time it’s financial. Nature. 2010 Oct 21;467(7318):885. PubMed PMID: 20962798.

Funding

  1. Brumfiel G. UK science funds in limbo. Nature. 2010 Oct 21;467(7318):894. PubMed PMID: 20962813.
  2. Gilbert N. Ireland defends research from cuts. Nature. 2010 Oct 21;467(7318):895. PubMed PMID: 20962814.
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2010-10-31 new articles we read this week

Monday, November 1, 2010

Genetics & Genomics

  1. Huang N, Lee I, Marcotte EM, Hurles ME. Characterising and predicting haploinsufficiency in the human genome. PLoS Genet. 2010 Oct 14;6(10):e1001154. PubMed PMID: 20976243; PubMed Central PMCID: PMC2954820.
  2. Sigurdsson MI, Jamshidi N, Steingrimsson E, Thiele I, Palsson BO. A detailed genome-wide reconstruction of mouse metabolism based on human Recon 1. BMC Syst Biol. 2010 Oct 19;4(1):140. [Epub ahead of print] PubMed PMID: 20959003.
  3. Pinna A, Soranzo N, de la Fuente A. From knockouts to networks: establishing direct cause-effect relationships through graph analysis. PLoS One. 2010 Oct 11;5(10):e12912. PubMed PMID: 20949005; PubMed Central PMCID: PMC2952592.

Retina & Eye

  1. Uribe RA, Gross JM. Id2a influences neuron and glia formation in the zebrafish retina by modulating retinoblast cell cycle kinetics. Development. 2010 Nov;137(22):3763-74. Epub 2010 Oct 13. PubMed PMID: 20943708.
  2. Davis DM, Dyer MA. Retinal progenitor cells, differentiation, and barriers to cell cycle reentry. Curr Top Dev Biol. 2010;93:175-88. PubMed PMID: 20959166.
  3. Fuhrmann S. Eye morphogenesis and patterning of the optic vesicle. Curr Top Dev Biol. 2010;93:61-84. PubMed PMID: 20959163; PubMed Central PMCID: PMC2958684.
  4. Kumar JP. Retinal determination the beginning of eye development. Curr Top Dev Biol. 2010;93:1-28. PubMed PMID: 20959161.
  5. Donovan M, Doonan F, Cotter TG. Differential roles of ERK1/2 and JNK in Retinal Development and Degeneration. J Neurochem. 2010 Oct 15. doi: 10.1111/j.1471-4159.2010.07056.x. [Epub ahead of print] PubMed PMID: 20950336.

Stem cells

  1. Chia NY, Chan YS, Feng B, Lu X, Orlov YL, Moreau D, Kumar P, Yang L, Jiang J, Lau MS, Huss M, Soh BS, Kraus P, Li P, Lufkin T, Lim B, Clarke ND, Bard F, Ng HH. A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature. 2010 Oct 17. [Epub ahead of print] PubMed PMID: 20953172.

Systems Biology

  1. Chang RL, Xie L, Xie L, Bourne PE, Palsson BØ. Drug off-target effects predicted using structural analysis in the context of a metabolic network model.  PLoS Comput Biol. 2010 Sep 23;6(9):e1000938. PubMed PMID: 20957118; PubMed Central PMCID: PMC2950675.

Zebrafish

  1. Hortopan GA, Dinday MT, Baraban SC. Spontaneous seizures and altered gene expression in GABA signaling pathways in a mind bomb mutant zebrafish. J Neurosci. 2010 Oct 13;30(41):13718-28. PubMed PMID: 20943912; PubMed Central PMCID: PMC2962868.
  2. Mara A, Holley SA. Oscillators and the emergence of tissue organization during zebrafish somitogenesis. Trends Cell Biol. 2007 Dec;17(12):593-9. Epub 2007 Nov 7. Review. PubMed PMID: 17988868.
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2010-10-23 articles we read this week

Monday, October 25, 2010

Eye diseases

  1. Moiseyev G, Nikolaeva O, Chen Y, Farjo K, Takahashi Y, Ma JX. Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17551-6. Epub 2010 Sep 27. PubMed PMID: 20876139.
  2. Hampton T. Genetic research provides insights into age-related macular degeneration. JAMA. 2010 Oct 13;304(14):1541-3. PubMed PMID: 20940375.

Stem cells

  1. Chamberlain SJ, Chen PF, Ng KY, Bourgois-Rocha F, Lemtiri-Chlieh F, Levine ES, Lalande M. Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes. Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17668-73. Epub 2010 Sep 27. PubMed PMID: 20876107.
  2. Stadtfeld M, Hochedlinger K. Induced pluripotency: history, mechanisms, and pplications. Genes Dev. 2010 Oct 15;24(20):2239-63. PubMed PMID: 20952534.

Medicine

  1. Hall WD, Mathews R, Morley KI. Being More Realistic about the Public Health Impact of Genomic Medicine. PLoS Med. 2010 Oct 12;7(10). pii: e1000347. PubMed PMID: 20967240.
  2. Lares MR, Rossi JJ, Ouellet DL. RNAi and small interfering RNAs in human disease therapeutic applications. Trends Biotechnol. 2010 Nov;28(11):570-9. Epub 2010 Sep 15. PubMed PMID: 20833440.
  3. Murray AB, Carson MJ, Morris CA, Beckwith J. Illusions of scientific legitimacy: misrepresented science in the direct-to-consumer genetic-testing marketplace. Trends Genet. 2010 Sep 7. [Epub ahead of print] PubMed PMID: 20828856.

Irx

  1. Yang ZQ, Liu G, Bollig-Fischer A, Giroux CN, Ethier SP. Transforming Properties of 8p11-12 Amplified Genes in Human Breast Cancer. Cancer Res. 2010 Oct 12. [Epub ahead of print] PubMed PMID: 20940404.

Education

  1. Kazilek C. Ask a biologist: bringing science to the public. PLoS Biol. 2010 Oct 12;8(10). pii: e1000458. PubMed PMID: 20967230.

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