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2010-11-20 New articles we read this week


  1. Shive HR, West RR, Embree LJ, Azuma M, Sood R, Liu P, Hickstein DD. brca2 in zebrafish ovarian development, spermatogenesis, and tumorigenesis. Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19350-5. Epub 2010 Oct 25. PubMed PMID: 20974951.
  2. Jain S, Heutink P. From single genes to gene networks: high-throughput-high-content screening for neurological disease. Neuron. 2010 Oct 21;68(2):207-17. Review. PubMed PMID: 20955929.

Eye Disease

  1. Linder B, Dill H, Hirmer A, Brocher J, Lee GP, Mathavan S, Bolz HJ, Winkler C, Laggerbauer B, Fischer U. Systemic splicing factor deficiency causes tissue-specific defects: A zebrafish model for Retinitis pigmentosa. Hum Mol Genet. 2010 Nov 3. [Epub ahead of print] PubMed PMID: 21051334.


  1. Lek M, Dias JM, Marklund U, Uhde CW, Kurdija S, Lei Q, Sussel L, Rubenstein JL, Matise MP, Arnold HH, Jessell TM, Ericson J. A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning. Development. 2010 Dec;137(23):4051-60. PubMed PMID: 21062862.
  2. Green AA, Kennaway JR, Hanna AI, Bangham JA, Coen E. Genetic Control of Organ Shape and Tissue Polarity. PLoS Biol. 2010 Nov 9;8(11):e1000537. PubMed PMID: 21085690.
  3. Cui ML, Copsey L, Green AA, Bangham JA, Coen E. Quantitative Control of Organ Shape by Combinatorial Gene Activity. PLoS Biol. 2010 Nov 9;8(11):e1000538. PubMed PMID: 21085695.

Eye Development

  1. Billings NA, Emerson MM, Cepko CL. Analysis of Thyroid Response Element Activity during Retinal Development. PLoS One. 2010 Oct 29;5(10):e13739. PubMed PMID: 21060789; PubMed Central PMCID: PMC2966421.
  2. Phillips MJ, Otteson DC. Differential expression of neuronal genes in Muller glia in two- and three-dimensional cultures. Invest Ophthalmol Vis Sci. 2010 Nov 4. [Epub ahead of print] PubMed PMID: 21051699.

Stem Cells

  1. Hanna JH, Saha K, Jaenisch R. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell. 2010 Nov 12;143(4):508-25. PubMed PMID: 21074044.
  2. Marchetto MC, Carromeu C, Acab A, Yu D, Yeo GW, Mu Y, Chen G, Gage FH, Muotri AR. A model for neural development and treatment of rett syndrome using humaninduced pluripotent stem cells. Cell. 2010 Nov 12;143(4):527-39. PubMed PMID: 21074045.


  1. Newman M, Lardelli M. A hyperactive sleeping beauty transposase enhances transgenesis in zebrafish embryos. BMC Res Notes. 2010 Nov 4;3(1):282. [Epub ahead of print] PubMed PMID: 21050486.


  1. Wyart M, Botstein D, Wingreen NS. Evaluating Gene Expression Dynamics Using Pairwise RNA FISH Data. PLoS Comput Biol. 2010 Nov 4;6(11):e1000979. PubMed PMID: 21079668; PubMed Central PMCID: PMC2973809.

Systems Biology

  1. Lehner B. Conflict between Noise and Plasticity in Yeast. PLoS Genet. 2010 Nov 4;6(11):e1001185. PubMed PMID: 21079670; PubMed Central PMCID: PMC2973811.
  2. Li J, Yuan Z, Zhang Z. The cellular robustness by genetic redundancy in budding yeast. PLoS Genet. 2010 Nov 4;6(11):e1001187. PubMed PMID: 21079672; PubMed Central PMCID: PMC2973813.

Ethics, Society and Legal Issues

  1. Johnson DG. The role of ethics in science and engineering. Trends Biotechnol. 2010 Sep 9. [Epub ahead of print] PubMed PMID: 20832883.