Development Kobayashi T, Zhang H, Tang WWC, Irie N, Withey S, Klisch D, Sybirna A, Dietmann S, Contreras DA, Webb R, Allegrucci C, Alberio R, Surani MA. Principles of early human development and germ cell program from conserved model systems. Nature. 2017 Jun 7. doi: 10.1038/nature22812. [Epub ahead of print] PubMed PMID: 28607482. Peter IS, […]
Tuesday, January 17, 2017
Evolution Gonzalez P, Uhlinger KR, Lowe CJ. The Adult Body Plan of Indirect Developing Hemichordates Develops by Adding a Hox-Patterned Trunk to an Anterior Larval Territory. Curr Biol. 2016 Dec 7. pii: S0960-9822(16)31273-8. doi: 10.1016/j.cub.2016.10.047. [Epub ahead of print] PubMed PMID: 27939313. Hejnol A, Vellutini BC. Larval Evolution: I’ll Tail You Later…. Curr Biol. 2017 […]
Wednesday, August 10, 2016
Genome editing Braun CJ, Bruno PM, Horlbeck MA, Gilbert LA, Weissman JS, Hemann MT. Versatile in vivo regulation of tumor phenotypes by dCas9-mediated transcriptional perturbation. Proc Natl Acad Sci U S A. 2016 Jun 20. pii: 201600582. [Epub ahead of print] PubMed PMID: 27325776. Regeneration Neves J, Zhu J, Sousa-Victor P, Konjikusic M, Riley R, […]
Stem cells Hou P, Li Y, Zhang X, Liu C, Guan J, Li H, Zhao T, Ye J, Yang W, Liu K, Ge J, Xu J, Zhang Q, Zhao Y, Deng H. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science. 2013 Aug 9;341(6146):651-4. doi: 10.1126/science.1239278. Epub 2013 Jul 18. PubMed PMID: […]
Filed in journal club
|
Also tagged brain, cone photoreceptors, CRISPR, CRISPR-CAS, induced pluripotent stem cells, iPSCs, memory, mitochondrial eve, neuroscience, olfaction, retina, small molecules, stem cells, vision, Y-chromosomal adam, zebrafish
|
Thursday, February 23, 2012
There is an interesting news article “Printing Muscle” from Technology Review about using 3-D printers to print muscle cells so that they may assume a 3-D shape that resembles muscle fiber. The idea sounds interesting, because one can potentially print tissues or even organs that have complicated cellular composition in 3-D for regenerative medicine.
Friday, November 25, 2011
From Discover magazine: “Helpful Mouse Fetuses Naturally Send Stem Cells to Mom to Fix Her Damaged Heart” The punchline is When a pregnant mouse has a heart attack, her fetus donates some of its stem cells to help rebuild the damaged heart tissue. The original article is available here. Kara RJ, Bolli P, Karakikes I, […]
Sunday, November 20, 2011
Medical Research *These two articles point out the problems of using animal models for research if the goal is to extract translational values and how mouse model, the gold standard for disease research, can actually be a poor reference standard because of the ways we want to standardize the biological tool for testing. Lynch VJ. […]
We have briefly touched the subject of stem cell research in the last journal club. The challenge of developing “stem cell” as a useful therapy is three fold: Turning the clock of a differentiated cell back to the very beginning. Guiding the resulting dedifferentiated “stem cells” or any kinds of “stem cells” to develop into […]