Leung Lab Blog

Development

1. Hamra FK. Gene targeting: Enter the rat. Nature. 2010 Sep 9;467(7312):161-3. PubMed PMID: 20829783.

Genomics

1. Bayley H. Nanotechnology: Holes with an edge. Nature. 2010 Sep 9;467(7312):164-5. PubMed PMID: 20829786.

Medicine

1. Willyard C. The real war on drugs. Nat Med. 2010 Sep;16(9):948-52. PubMed PMID: 20823866.
2. Dolgin E. Personalized investigation. Nat Med. 2010 Sep;16(9):953-5. PubMed PMID: 20823867.
3. Kaynar AM, Shapiro SD. NET loss of air in cystic fibrosis. Nat Med. 2010 Sep;16(9):967-9. PubMed PMID: 20823877.
4. Ellis LM, Fidler IJ. Finding the tumor copycat: Therapy fails, patients don’t. Nat Med. 2010 Sep;16(9):974-5. PubMed PMID: 20823880.
5. Van Dyke T. Finding the tumor copycat: Approximating a human cancer. Nat Med. 2010 Sep;16(9):976-7. PubMed PMID: 20823881.
6. Bonham VL, Dover GJ, Brody LC. Screening student athletes for sickle cell trait – a social and clinical experiment. N Engl J Med. 2010 Sep 9;363(11):997-9. PubMed PMID: 20825310.
7. Rezaie R, Singer PA. Global health or global wealth? Nat Biotechnol. 2010 Sep;28(9):907-9. PubMed PMID: 20829824.

Retinal development

1. Prasov L, Brown NL, Glaser T. A critical analysis of Atoh7 (Math5) mRNA splicing in the developing mouse retina. PLoS One. 2010 Aug 24;5(8). pii: e12315. PubMed PMID: 20808762; PubMed Central PMCID: PMC2927423.
2. Erickson T, French CR, Waskiewicz AJ. Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system. Neural Dev. 2010 Sep 1;5(1):22. [Epub ahead of print] PubMed PMID: 20809932.
3. Ben Fredj N, Hammond S, Otsuna H, Chien CB, Burrone J, Meyer MP. Synaptic activity and activity-dependent competition regulates axon arbor maturation, growth arrest, and territory in the retinotectal projection. J Neurosci. 2010 Aug 11;30(32):10939-51. PubMed PMID: 20702722.

Systems biology  & Gene regulatory network

1. Shoval O, Goentoro L, Hart Y, Mayo A, Sontag E, Alon U. Fold-change detection and scalar symmetry of sensory input fields. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15995-6000. Epub 2010 Aug 20. PubMed PMID: 20729472.
2. Serb JM, Orr MC, West Greenlee MH. Using evolutionary conserved modules in gene networks as a strategy to leverage high throughput gene expression queries. PLoS One. 2010 Sep 2;5(9). pii: e12525. PubMed PMID: 20824082; PubMed Central PMCID: PMC2932711.
3. de Bivort BL. Derivation of large-scale cellular regulatory networks from biological time series data. Methods Mol Biol. 2010;662:149-65. PubMed PMID: 20824470.
4. Kazemian M, Blatti C, Richards A, McCutchan M, Wakabayashi-Ito N, Hammonds AS, Celniker SE, Kumar S, Wolfe SA, Brodsky MH, Sinha S. Quantitative analysis of the Drosophila segmentation regulatory network using pattern generating potentials. PLoS Biol. 2010 Aug 17;8(8). pii: e1000456. PubMed PMID: 20808951; PubMed Central PMCID: PMC2923081.
5. Kuttykrishnan S, Sabina J, Langton LL, Johnston M, Brent MR. A quantitative model of glucose signaling in yeast reveals an incoherent feed forward loop leading to a specific, transient pulse of transcription. Proc Natl Acad Sci U S A. 2010 Sep 1. [Epub ahead of print] PubMed PMID: 20810924.
6. Sun L, Becskei A. Systems biology: The cost of feedback control. Nature. 2010 Sep 9;467(7312):163-4. PubMed PMID: 20829785.
7. Eldar A, Elowitz MB. Functional roles for noise in genetic circuits. Nature. 2010 Sep 9;467(7312):167-73. PubMed PMID: 20829787.
8. Lestas I, Vinnicombe G, Paulsson J. Fundamental limits on the suppression of molecular fluctuations. Nature. 2010 Sep 9;467(7312):174-8. PubMed PMID: 20829788.

Toxicology

1. Larsen MG, Baatrup E. Functional behavior and reproduction in androgenic sex reversed zebrafish (Danio rerio). Environ Toxicol Chem. 2010 Aug;29(8):1828-33. PubMed PMID: 20821638.