Leung Lab Blog

Systems biology and Genomics

1. Chen WW, Niepel M, Sorger PK. Classic and contemporary approaches to modeling biochemical reactions. Genes Dev. 2010 Sep 1;24(17):1861-75. PubMed PMID: 20810646.
2. Schatz MC, Delcher AL, Salzberg SL. Assembly of large genomes using second-generation sequencing. Genome Res. 2010 Sep;20(9):1165-73. Epub 2010 May 27. PubMed PMID: 20508146.
3. Zhuravel D, Fraser D, St-Pierre S, Tepliakova L, Pang WL, Hasty J, Kærn M. Phenotypic impact of regulatory noise in cellular stress-response pathways. Syst Synth Biol. 2010 Jun;4(2):105-116.
4. Levin JZ, Yassour M, Adiconis X, Nusbaum C, Thompson DA, Friedman N, Gnirke A, Regev A. Comprehensive comparative analysis of strand-specific RNA sequencing methods. Nat Methods. 2010 Sep;7(9):709-15. Epub 2010 Aug 15. PubMed PMID: 20711195.

Imaging

1. Peng H, Ruan Z, Long F, Simpson JH, Myers EW. V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets. Nat Biotechnol. 2010 Apr;28(4):348-53. Epub 2010 Mar 14. PubMed PMID: 20231818; PubMed Central PMCID: PMC2857929.
2. Peng H, Ruan Z, Atasoy D, Sternson S. Automatic reconstruction of 3D neuron structures using a graph-augmented deformable model. Bioinformatics. 2010 Jun 15;26(12):i38-46. PubMed PMID: 20529931; PubMed Central PMCID: PMC2881396.
3. Liu X, Long F, Peng H, Aerni SJ, Jiang M, Sánchez-Blanco A, Murray JI, Preston E, Mericle B, Batzoglou S, Myers EW, Kim SK. Analysis of cell fate from single-cell gene expression profiles in C. elegans. Cell. 2009 Oct 30;139(3):623-33. PubMed PMID: 19879847.
4. Long F, Peng H, Liu X, Kim SK, Myers E. A 3D digital atlas of C. elegans and its application to single-cell analyses. Nat Methods. 2009 Sep;6(9):667-72. Epub 2009 Aug 16. PubMed PMID: 19684595; PubMed Central PMCID: PMC2882208.
5. Peng H, Long F, Liu X, Kim SK, Myers EW. Straightening Caenorhabditis elegans images. Bioinformatics. 2008 Jan 15;24(2):234-42. Epub 2007 Nov 19. PubMed PMID: 18025002.

Medicine

1. Physician, know thyself. Lancet. 2010 Sep 4;376(9743):743. PubMed PMID: 20816524.

Eye disease

1. Li L, Nakaya N, Chavali VR, Ma Z, Jiao X, Sieving PA, Riazuddin S, Tomarev SI, Ayyagari R, Riazuddin SA, Hejtmancik JF.  A Mutation in ZNF513, a Putative Regulator of Photoreceptor Development, Causes Autosomal-Recessive Retinitis Pigmentosa. Am J Hum Genet. 2010 Aug 25;. [Epub ahead of print] PMID: 20797688

Neuroscience and behaviour

1. Feitl KE, Ngo V, McHenry MJ.  Are fish less responsive to a flow stimulus when swimming? J Exp Biol. 2010 Sep 15;213(Pt 18):3131-7. PubMed PMID: 20802114.
2. Youk H, van Oudenaarden A. Microbiology: Altruistic defence. Nature. 2010 Sep 2;467(7311):34-5. PubMed PMID: 20811443.

Education

1. Ditty JL, Kvaal CA, Goodner B, Freyermuth SK, Bailey C, Britton RA, Gordon SG, Heinhorst S, Reed K, Xu Z, Sanders-Lorenz ER, Axen S, Kim E, Johns M, Scott K, Kerfeld CA. Incorporating genomics and bioinformatics across the life sciences curriculum. PLoS Biol. 2010 Aug 10;8(8):e1000448. PubMed PMID: 20711478; PubMed Central PMCID: PMC2919421.

Stem cell

1. Buxboim A, Discher DE. Stem cells feel the difference. Nat Methods. 2010 Sep;7(9):695-7. PubMed PMID: 20805798.