Leung Lab Blog

Behaviour

1. Li L. Zebrafish mutants: behavioral genetic studies of visual system defects. Dev Dyn. 2001 Aug;221(4):365-72. Review. PubMed PMID: 11500973.
2. Orger MB, Gahtan E, Muto A, Page-McCaw P, Smear MC, Baier H. Behavioral screening assays in zebrafish. Methods Cell Biol. 2004;77:53-68. PubMed PMID: 15602905.

Cancer

1. Feitsma H, Cuppen E. Zebrafish as a cancer model. Mol Cancer Res. 2008 May;6(5):685-94. Review. PubMed PMID: 18505914.

Gene expression

1. Ohlsson R. Gene expression: The coherent Mediator. Nature. 2010 Sep 23;467(7314):406-7. PubMed PMID: 20864988.

Patterning

1. Kondo S, Miura T. Reaction-Diffusion Model as a Framework for Understanding Biological Pattern Formation. Science. 2010 Sep 24; 329; 1616-1620.

Evolution

1. Burke MK, Dunham JP, Shahrestani P, Thornton KR, Rose MR, Long AD. Genome-wide analysis of a long-term evolution experiment with Drosophila. Nature. 2010 Sep 30;467(7315):587-90. Epub 2010 Sep 15. PubMed PMID: 20844486.

Medicine

1. Cooke M. Science for Physicians. Science. 2010 Sep 24; 329; 1573.

Gene regulatory network & Systems biology

1. Acar M, et al., A General Mechanism for Network-Dosage Compensation in Gene Circuits. Science. 2010 Sep 24; 329; 1656-1660.
2. Young NM, Chong HJ, Hu D, Hallgrímsson B, Marcucio RS. Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape. Development. 2010 Oct;137(20):3405-9. Epub 2010 Sep 8. PubMed PMID: 20826528.
3. Toettcher JE, Mock C, Batchelor E, Loewer A, Lahav G. A synthetic-natural hybrid oscillator in human cells. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):17047-52. Epub 2010 Sep 13. PubMed PMID: 20837528.
4. Bandyopadhyay et al., A human MAP kinase interactome. Nat. Method. 2010; 7:801-805.
5. Neems D, Kosak ST. Turning down the volume on transcriptional noise. Nat Cell Biol. 2010 Oct;12(10):929-31. PubMed PMID: 20885421.
6. Giacomantonio CE, Goodhill GJ. A Boolean model of the gene regulatory network underlying Mammalian cortical area development. PLoS Comput Biol. 2010 Sep 16;6(9). pii: e1000936. PubMed PMID: 20862356; PubMed Central PMCID: PMC2940723.
7. Stormo GD, Zhao Y. Determining the specificity of protein-DNA interactions. Nat Rev Genet. 2010 Sep 28. [Epub ahead of print] PubMed PMID: 20877328.
8. Alon U. Network motifs: theory and experimental approaches. Nat Rev Genet. 2007 Jun;8(6):450-61. Review. PubMed PMID: 17510665.

Retina

1. Allison WT, Barthel LK, Skebo KM, Takechi M, Kawamura S, Raymond PA. Ontogeny of cone photoreceptor mosaics in zebrafish. J Comp Neurol. 2010 Oct 15;518(20):4182-95. PubMed PMID: 20878782.

Delta-Notch signal transduction

1. Matsuda M, Chitnis AB. Atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the posterior lateral line primordium in zebrafish. Development. 2010 Oct;137(20):3477-87. PubMed PMID: 20876657.
2. Milán M, Cohen SM.  Notch signaling: filopodia dynamics confer robustness. Curr Biol. 2010 Sep 28;20(18):R802-4. PMID: 20869605 [PubMed – in process]
3. Del Debbio CB, Balasubramanian S, Parameswaran S, Chaudhuri A, Qiu F, Ahmad I. Notch and Wnt signaling mediated rod photoreceptor regeneration by Müller cells in adult mammalian retina. PLoS One. 2010 Aug 26;5(8):e12425. PubMed PMID: 20865053; PubMed Central PMCID: PMC2928741.

Research funding

1. Powell K. Research funding: Making the cut. Nature. 2010 Sep 23;467(7314):383-5. PubMed PMID: 20864969.

Research ethics

1. Cyranoski D. Brawl in Beijing. Nature. 2010 Sep 30;467(7315):511. PubMed PMID: 20881985.
2. Maher B. Research integrity: Sabotage! Nature. 2010 Sep 30;467(7315):516-8. PubMed PMID: 20881988.