Just saw this from a friend’s share. It is a great TED talk by Uri Alon on his experience on doing innovative science.
His work has inspired many including myself. Here are a few seminal papers by his groups.
- Milo R, Shen-Orr S, Itzkovitz S, Kashtan N, Chklovskii D, Alon U. Network motifs: simple building blocks of complex networks. Science. 2002 Oct 25;298(5594):824-7. PubMed PMID: 12399590.
- Shen-Orr SS, Milo R, Mangan S, Alon U. Network motifs in the transcriptional regulation network of Escherichia coli. Nat Genet. 2002 May;31(1):64-8. Epub 2002 Apr 22. PubMed PMID: 11967538.
- Alon U. Network motifs: theory and experimental approaches. Nat Rev Genet. 2007 Jun;8(6):450-61. Review. PubMed PMID: 17510665.