Medicine An interesting paper talking about an electronic skin that can do multiple tasks. Kim DH, Lu N, Ma R, Kim YS, Kim RH, Wang S, Wu J, Won SM, Tao H, Islam A, Yu KJ, Kim TI, Chowdhury R, Ying M, Xu L, Li M, Chung HJ, Keum H, McCormick M, Liu P, Zhang […]
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Retinal development Brzezinski JA 4th, Kim EJ, Johnson JE, Reh TA. Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina.Development. 2011 Aug;138(16):3519-31. Epub 2011 Jul 19. PubMed PMID: 21771810. Ford KJ, Feller MB. Assembly and disassembly of a retinal cholinergic network.Vis Neurosci. 2011 Jul 26:1-11. [Epub ahead of print] PubMed PMID: 21787461. […]
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Animal model Aitman TJ, Boone C, Churchill GA, Hengartner MO, Mackay TF, Stemple DL. The future of model organisms in human disease research. Nat Rev Genet. 2011 Jul18;12(8):575-82. doi: 10.1038/nrg3047. PubMed PMID: 21765459. Thomas JL, Vihtelic TS, Dendekker AD, Willer G, Luo X, Murphy TR, Gregg RG, Hyde DR, Thummel R. The loss of vacuolar […]
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Delta-Notch, signal transduction Ohata S, Aoki R, Kinoshita S, Yamaguchi M, Tsuruoka-Kinoshita S, Tanaka H, Wada H, Watabe S, Tsuboi T, Masai I, Okamoto H. Dual roles of Notch in regulation of apically restricted mitosis and apicobasal polarity of neuroepithelial cells. Neuron. 2011 Jan 27;69(2):215-30. PubMed PMID: 21262462. Ethical, Legal and Social Issues Mismeasure for […]
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Delta-Notch Niwa Y, Shimojo H, Isomura A, González A, Miyachi H, Kageyama R. Different types of oscillations in Notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis. Genes Dev. 2011 Jun 1;25(11):1115-20. PubMed PMID: 21632822. Retina Robinson R. After 40 years, retina reveals it uses positive feedback, as well as negative. PLoS Biol. 2011 […]
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Gene regulatory network Walhout AJ. What does biologically meaningful mean? A perspective on generegulatory network validation. Genome Biol. 2011 Apr 11;12(4):109. [Epub ahead ofprint] PubMed PMID: 21489330. Su WL, Kleinhanz RR, Schadt EE. Characterizing the role of miRNAs within gene regulatory networks using integrative genomics techniques. Mol Syst Biol. 2011 May 24;7:490. PubMed PMID: 21613979. […]
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Eye diseases Sheffield VC, Stone EM. Genomics and the eye. N Engl J Med. 2011 May 19;364(20):1932-42. PubMed PMID: 21591945. Regeneration Tu S, Johnson SL. Fate restriction in the growing and regenerating zebrafish fin. Dev Cell. 2011 May 17;20(5):725-32. PubMed PMID: 21571228; PubMed CentralPMCID: PMC3096007. Knopf F, Hammond C, Chekuru A, Kurth T, Hans S, […]
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Genomics/ next-generation sequencing Anders S, Huber W. Differential expression analysis for sequence count data.Genome Biol. 2010;11(10):R106. Epub 2010 Oct 27. PubMed PMID: 20979621. Gresham D, Boer VM, Caudy A, Ziv N, Brandt NJ, Storey JD, Botstein D. System-level analysis of genes and functions affecting survival during nutrient starvation in Saccharomyces cerevisiae. Genetics. 2011 Jan;187(1):299-317. Epub2010 […]
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Genomics Nagano T, Fraser P. No-Nonsense Functions for Long Noncoding RNAs. Cell. 2011 Apr 15;145(2):178-81. PubMed PMID: 21496640. Mak HC. John storey. Nat Biotechnol. 2011 Apr;29(4):331-3. PubMed PMID: 21478851. A nice discussion by John Storey on the challenges of normalization and analysis of next generation sequencing data for RNA-Seq. Systems biology Oleksiuk O, Jakovljevic V, […]
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Education Nature Magazine has published a series of papers that discuss “The Future of The PhD“. Another discussion of the challenges that PhD students encounter and a debate on whether a doctoral degree should be a training for job or a training for scientific thinking. The discussions from the readers under each article on the […]
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