Leung Lab Blog

Development

1. Eiraku M, Takata N, Ishibashi H, Kawada M, Sakakura E, Okuda S, Sekiguchi K, Adachi T, Sasai Y. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature. 2011 Apr 7;472(7341):51-6. PubMed PMID: 21475194.
   1. Commentary: Ali RR, Sowden JC. Regenerative medicine: DIY eye. Nature. 2011 Apr 7;472(7341):42-3. PubMed PMID: 21475187.
   2. News report from the Telegraph. “Scientists grow ’embryonic eye’ in test tube“.
   • A whole eye cup with properly laminated retina and RPE can spontaneously generate from mouse embryonic stem cell culture!

Eye disease

1. Morris AC, Forbes-Osborne MA, Pillai LS, Fadool JM. Microarray Analysis of XOPS-mCFP Zebrafish Retina Identifies Genes Associated with Rod Photoreceptor Degeneration and Regeneration. Invest Ophthalmol Vis Sci. 2011 Apr6;52(5):2255-66. Print 2011 Apr. PubMed PMID: 21217106.
2. Stujenske JM, Dowling JE, Emran F. The Bugeye Mutant Zebrafish Exhibits Visual Deficits that Arise with the Onset of an Enlarged Eye Phenotype. Invest Ophthalmol Vis Sci. 2011 Apr 1. [Epub ahead of print] PubMed PMID: 21460263.

Retinal development

1. Glaschke A, Weiland J, Del Turco D, Steiner M, Peichl L, Glösmann M. Thyroid hormone controls cone opsin expression in the retina of adult rodents. JNeurosci. 2011 Mar 30;31(13):4844-51. PubMed PMID: 21451022.

Ethical, Social and Legal Issues

1. Hayden EC. Patent dispute threatens US Alzheimer’s research. Nature. 2011 Apr 7;472(7341):20. PubMed PMID: 21475170.

Education

1. Nayar A. Developing world: educating India. Nature. 2011 Apr 7;472(7341):24-6. PubMed PMID: 21475172.

Cancer

1. Navin N, Kendall J, Troge J, Andrews P, Rodgers L, McIndoo J, Cook K, Stepansky A, Levy D, Esposito D, Muthuswamy L, Krasnitz A, McCombie WR, Hicks J, Wigler M. Tumour evolution inferred by single-cell sequencing. Nature. 2011 Apr7;472(7341):90-4. Epub 2011 Mar 13. PubMed PMID: 21399628.

Neurobehavior

1. Liu Y, Jiang Y, Si Y, Kim JY, Chen ZF, Rao Y. Molecular regulation of sexual preference revealed by genetic studies of 5-HT in the brains of male mice. Nature. 2011 Apr 7;472(7341):95-9. Epub 2011 Mar 23. PubMed PMID: 21441904.