Leung Lab Blog

Origin of Life

1. Wolfe-Simon F, Blum JS, Kulp TR, Gordon GW, Hoeft SE, Pett-Ridge J, Stolz JF, Webb SM, Weber PK, Davies PC, Anbar AD, Oremland RS. A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus. Science. 2010 Dec 2. [Epub ahead of print] PubMed PMID: 21127214.
   • News coverage on BBC

Image analysis

1. Shamir L, Delaney JD, Orlov N, Eckley DM, Goldberg IG. Pattern recognition software and techniques for biological image analysis. PLoS Comput Biol. 2010 Nov 24;6(11):e1000974. PubMed PMID: 21124870.
2. Wollman R, Stuurman N. High throughput microscopy: from raw images to discoveries. J Cell Sci. 2007 Nov 1;120(Pt 21):3715-22. Review. PubMed PMID: 17959627.
3. Carpenter AE, Jones TR, Lamprecht MR, Clarke C, Kang IH, Friman O, Guertin DA, Chang JH, Lindquist RA, Moffat J, Golland P, Sabatini DM. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol. 2006;7(10):R100. Epub 2006 Oct 31. PubMed PMID: 17076895; PubMed Central PMCID: PMC1794559.
4. Jones TR, Kang IH, Wheeler DB, Lindquist RA, Papallo A, Sabatini DM, Golland P, Carpenter AE. CellProfiler Analyst: data exploration and analysis software for complex image-based screens. BMC Bioinformatics. 2008 Nov 15;9:482. PubMed PMID: 19014601; PubMed Central PMCID: PMC2614436.
5. Jones TR, Carpenter AE, Lamprecht MR, Moffat J, Silver SJ, Grenier JK, Castoreno AB, Eggert US, Root DE, Golland P, Sabatini DM. Scoring diverse cellular morphologies in image-based screens with iterative feedback and machine learning. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1826-31. Epub 2009 Feb 2.  PubMed PMID: 19188593; PubMed Central PMCID: PMC2634799.
6. Lamprecht MR, Sabatini DM, Carpenter AE. CellProfiler: free, versatile software for automated biological image analysis. Biotechniques. 2007 Jan;42(1):71-5. PubMed PMID: 17269487.

Neuroscience

1. Schwab ME. How hard is the CNS hardware? Nat Neurosci. 2010 Dec;13(12):1444-6. PubMed PMID: 21102566.

Retina

1. Fischer AJ, Bongini R. Turning müller glia into neural progenitors in the retina. Mol Neurobiol. 2010 Dec;42(3):199-209. Epub 2010 Nov 20. PubMed PMID:21088932.

Genomics

1. Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol. 2010 Oct 27;11(10):R106. [Epub ahead of print] PubMed PMID: 20979621.
2. Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R. Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci U S A. 2010 Nov 24. [Epub ahead of print] PubMed PMID: 21106759.

Brg1

1. Watanabe T, Semba S, Yokozaki H. Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cells. Br J Cancer. 2010 Nov 23. [Epub ahead of print] PubMed PMID: 21102582.

Physiology

1. Ng SF, Lin RC, Laybutt DR, Barres R, Owens JA, Morris MJ. Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring. Nature. 2010 Oct 21;467(7318):963-6. PubMed PMID: 20962845.