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2011-08-21 New articles we read this week

Medicine

An interesting paper talking about an electronic skin that can do multiple tasks.

  1. Kim DH, Lu N, Ma R, Kim YS, Kim RH, Wang S, Wu J, Won SM, Tao H, Islam A, Yu KJ, Kim TI, Chowdhury R, Ying M, Xu L, Li M, Chung HJ, Keum H, McCormick M, Liu P, Zhang YW, Omenetto FG, Huang Y, Coleman T, Rogers JA. Epidermal electronics. Science. 2011 Aug 12;333(6044):838-43. PubMed PMID: 21836009.
    • Commentary: Ma Z. Materials science. An electronic second skin. Science. 2011 Aug 12;333(6044):830-1. PubMed PMID: 21836004.

Genomics

  1. Gonzalez-Roca E, Garcia-Albéniz X, Rodriguez-Mulero S, Gomis RR, Kornacker K,  Auer H. Accurate expression profiling of very small cell populations. PLoS One. 2010 Dec 28;5(12):e14418. PubMed PMID: 21203435; PubMed Central PMCID:
    PMC3010985.

Disease Gene Mapping

  1. Ozgül RK, Siemiatkowska AM, Yücel D, Myers CA, Collin RW, Zonneveld MN, Beryozkin A, Banin E, Hoyng CB, van den Born LI; The European Retinal Disease Consortium, Bose R, Shen W, Sharon D, Cremers FP, Klevering BJ, den Hollander AI, Corbo JC. Exome Sequencing and cis-Regulatory Mapping Identify Mutations in MAK, a Gene Encoding a Regulator of Ciliary Length, as a Cause of Retinitis Pigmentosa. Am J Hum Genet. 2011 Aug 12;89(2):253-264. PubMed PMID: 21835304.

Genetics

  • This is a series of papers about TALENs (Transcription Activator-Like Effector Nucleases), a new way of gene disruption that can potentially replace ZFNS (Zinc Finger Nucleases).
  1. Move over ZFNs. Nat Biotechnol. 2011 Aug 5;29(8):681-4. doi: 10.1038/nbt.1935. PubMed PMID: 21822235.
  2. Tesson L, Usal C, Ménoret S, Leung E, Niles BJ, Remy S, Santiago Y, Vincent AI, Meng X, Zhang L, Gregory PD, Anegon I, Cost GJ. Knockout rats generated by embryo microinjection of TALENs. Nat Biotechnol. 2011 Aug 5;29(8):695-6. doi: 10.1038/nbt.1940. PubMed PMID: 21822240.
  3. Sander JD, Cade L, Khayter C, Reyon D, Peterson RT, Joung JK, Yeh JR. Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Nat Biotechnol. 2011 Aug 5;29(8):697-8. doi: 10.1038/nbt.1934. PubMed PMID: 21822241; PubMed Central PMCID: PMC3154023.
  4. Huang P, Xiao A, Zhou M, Zhu Z, Lin S, Zhang B. Heritable gene targeting in zebrafish using customized TALENs. Nat Biotechnol. 2011 Aug 5;29(8):699-700. doi: 10.1038/nbt.1939. PubMed PMID: 21822242.
  5. Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R. Genetic engineering of human pluripotent cells  using TALE nucleases. Nat Biotechnol. 2011 Jul 7;29(8):731-4. doi: 10.1038/nbt.1927. PubMed PMID: 21738127; PubMed Central PMCID: PMC3152587.

Delta-Notch Signal Transduction

  1. Andersson ER, Sandberg R, Lendahl U. Notch signaling: simplicity in design, versatility in function. Development. 2011 Sep;138(17):3593-612. PubMed PMID: 21828089.
  2. Tossell K, Kiecker C, Wizenmann A, Lang E, Irving C. Notch signalling stabilises boundary formation at the midbrain-hindbrain organiser. Development. 2011 Sep;138(17):3745-57. Epub 2011 Jul 27. PubMed PMID: 21795283.

Gene regulatory network

  1. Karczewski KJ, Tatonetti NP, Landt SG, Yang X, Slifer T, Altman RB, Snyder M.  Cooperative transcription factor associations discovered using regulatory variation. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13353-8. Epub 2011 Jul 26. PubMed PMID: 21828005.

Irx

  1. Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olguín P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, Hui CC, Bruneau BG, Backx PH. Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proc Natl Acad Sci U S A. 2011 Aug 8. [Epub ahead of print] PubMed PMID: 21825130.

Eye disease

  1.  Nelson BR, Ueki Y, Reardon S, Karl MO, Georgi S, Hartman BH, Lamba DA, Reh TA. Genome-wide analysis of müller glial differentiation reveals a requirement for notch signaling in postmitotic cells to maintain the glial fate. PLoS One. 2011;6(8):e22817. Epub 2011 Aug 2. PubMed PMID: 21829655.

Regeneration

  1. Bermingham-McDonogh O, Reh TA. Regulated reprogramming in the regeneration of  sensory receptor cells. Neuron. 2011 Aug 11;71(3):389-405. PubMed PMID: 21835338.