{"id":75,"date":"2009-05-21T07:49:09","date_gmt":"2009-05-21T12:49:09","guid":{"rendered":"https:\/\/leung.bio.purdue.edu\/blog\/?p=75"},"modified":"2009-07-16T07:40:37","modified_gmt":"2009-07-16T12:40:37","slug":"the-origin-of-rna","status":"publish","type":"post","link":"https:\/\/leung.bio.purdue.edu\/blog\/the-origin-of-rna\/","title":{"rendered":"The origin of RNA"},"content":{"rendered":"<blockquote><p>A fundamental but elusive step in the early evolution of life on Earth has been replicated in a laboratory.<\/p>\n<p>Researchers synthesized the basic ingredients of RNA, a molecule from which the simplest self-replicating structures are made. Until now, they couldn\u2019t explain how these ingredients might have formed.<\/p>\n<p>&#8230;.<\/p>\n<p>No matter how they combined the ingredients \u2014 a sugar, a phosphate, and one of four different nitrogenous molecules, or nucleobases \u2014 ribonucleotides just wouldn\u2019t form. Sutherland\u2019s team took a different approach &#8220;and successfully synthesized RNA&#8221; in a laboratory conditions resembled those of the life-originating \u201cwarm little pond\u201d.<\/p><\/blockquote>\n<p><em>References:<\/em><\/p>\n<p>Life\u2019s First Spark Re-Created in the Laboratory [<a href=\"http:\/\/www.wired.com\/wiredscience\/2009\/05\/ribonucleotides\/\">Wired<\/a>]<\/p>\n<p>Powner MW, Gerland B, Sutherland JD. Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions. <span class=\"journalname\" title=\"Nature\">Nature<\/span>. 2009 May 14;459(7244):239-42. [<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19444213\">PubMed<\/a>][<a href=\"http:\/\/www.nature.com\/nature\/journal\/v459\/n7244\/abs\/nature08013.html\">Nature<\/a>]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A fundamental but elusive step in the early evolution of life on Earth has been replicated in a laboratory. Researchers synthesized the basic ingredients of RNA, a molecule from which the simplest self-replicating structures are made. Until now, they couldn\u2019t explain how these ingredients might have formed. &#8230;. No matter how they combined the ingredients [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[16,6],"tags":[447,14],"class_list":["post-75","post","type-post","status-publish","format-standard","hentry","category-evolution","category-news","tag-evolution","tag-rna"],"_links":{"self":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/75","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/comments?post=75"}],"version-history":[{"count":8,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/75\/revisions"}],"predecessor-version":[{"id":77,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/75\/revisions\/77"}],"wp:attachment":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/media?parent=75"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/categories?post=75"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/tags?post=75"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}