{"id":1499,"date":"2013-09-29T16:19:41","date_gmt":"2013-09-29T20:19:41","guid":{"rendered":"http:\/\/www.bio.purdue.edu\/lab\/leung\/blog\/?p=1499"},"modified":"2013-09-29T16:19:41","modified_gmt":"2013-09-29T20:19:41","slug":"2013-09-29-new-articles-we-read-this-week","status":"publish","type":"post","link":"https:\/\/leung.bio.purdue.edu\/blog\/2013-09-29-new-articles-we-read-this-week\/","title":{"rendered":"2013-09-29 new articles we read this week"},"content":{"rendered":"<p><strong>Stem cells<\/strong><\/p>\n<ol>\n<li><span style=\"font-size: 13px; line-height: 19px;\">Abad M, Mosteiro L, Pantoja C, Ca\u00f1amero M, Rayon T, Ors I, Gra\u00f1a O, Meg\u00edas D, Dom\u00ednguez O, Mart\u00ednez D, Manzanares M, Ortega S, Serrano M. Reprogramming in vivo\u00a0produces teratomas and iPS cells with totipotency features. Nature. 2013 Sep 11. doi: 10.1038\/nature12586. [Epub ahead of print] PubMed PMID: 24025773.<\/span>\n<ul>\n<li><span style=\"font-size: 13px; line-height: 19px;\">Commentary: De Los Angeles A, Daley GQ. Stem cells: Reprogramming in situ. Nature. 2013\u00a0Sep 11. doi: 10.1038\/nature12559. [Epub ahead of print] PubMed PMID: 24025771.<\/span><\/li>\n<li><span style=\"font-size: 13px; line-height: 19px;\">News coverage: <a href=\"http:\/\/www.the-scientist.com\/?articles.view\/articleNo\/37452\/title\/More-Primitive-Stem-Cells-Produced\/\">More-Primitive Stem Cells Produced<\/a><\/span><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<p><a href=\"http:\/\/www.improbable.com\/ig\/winners\/#ig2013\"><strong>Ig Nobel price 2013<\/strong><\/a><\/p>\n<p><strong>Medicine<\/strong><\/p>\n<ol>\n<li><span style=\"font-size: 13px; line-height: 19px;\">Sridhar S, Begom S, Bermingham A, Hoschler K, Adamson W, Carman W, Bean T,\u00a0Barclay W, Deeks JJ, Lalvani A. Cellular immune correlates of protection against symptomatic pandemic influenza. Nat Med. 2013 Sep 22. doi: 10.1038\/nm.3350. [Epub\u00a0ahead of print] PubMed PMID: 24056771.<\/span>\n<ul>\n<li><span style=\"font-size: 13px; line-height: 19px;\">News coverage: <a href=\"http:\/\/www.bbc.co.uk\/news\/health-24175030\">Scientists take big step towards universal flu vaccine<\/a><\/span><span style=\"font-size: 13px; line-height: 19px;\">\u00a0<\/span><\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<p><strong>Development<\/strong><\/p>\n<ol>\n<li><span style=\"font-size: 13px; line-height: 19px;\">Lee MT, Bonneau AR, Takacs CM, Bazzini AA, Divito KR, Fleming ES, Giraldez AJ.\u00a0Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the\u00a0maternal-to-zygotic transition. Nature. 2013 Sep 22. doi: 10.1038\/nature12632.\u00a0[Epub ahead of print] PubMed PMID: 24056933.<\/span><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><strong>Genetics<\/strong><\/p>\n<ol>\n<li><span style=\"font-size: 13px; line-height: 19px;\">Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA,\u00a0Inoue A, Matoba S, Zhang Y, Zhang F. Double Nicking by RNA-Guided CRISPR Cas9 for\u00a0Enhanced Genome Editing Specificity. Cell. 2013 Sep 12;154(6):1380-9. doi:\u00a010.1016\/j.cell.2013.08.021. Epub 2013 Aug 29. PubMed PMID: 23992846.<\/span><\/li>\n<li><span style=\"font-size: 13px; line-height: 19px;\">Yang H, Wang H, Shivalila CS, Cheng AW, Shi L, Jaenisch R. One-Step Generation\u00a0of Mice Carrying Reporter and Conditional Alleles by CRISPR\/Cas-Mediated Genome\u00a0Engineering. Cell. 2013 Sep 12;154(6):1370-9. doi: 10.1016\/j.cell.2013.08.022.\u00a0Epub 2013 Aug 29. PubMed PMID: 23992847.<\/span><\/li>\n<li><span style=\"font-size: 13px; line-height: 19px;\">Mali P, Aach J, Stranges PB, Esvelt KM, Moosburner M, Kosuri S, Yang L, Church\u00a0<\/span><span style=\"font-size: 13px; line-height: 19px;\">GM. CAS9 transcriptional activators for target specificity screening and paired\u00a0<\/span><span style=\"font-size: 13px; line-height: 19px;\">nickases for cooperative genome engineering. Nat Biotechnol. 2013\u00a0<\/span><span style=\"font-size: 13px; line-height: 19px;\">Sep;31(9):833-8. doi: 10.1038\/nbt.2675. Epub 2013 Aug 1. PubMed PMID: 23907171.<\/span><\/li>\n<li><span style=\"font-size: 13px; line-height: 19px;\">DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM. Genome engineering\u00a0<\/span><span style=\"font-size: 13px; line-height: 19px;\">in Saccharomyces cerevisiae using CRISPR-Cas systems. Nucleic Acids Res. 2013\u00a0<\/span><span style=\"font-size: 13px; line-height: 19px;\">Apr;41(7):4336-43. doi: 10.1093\/nar\/gkt135. Epub 2013 Mar 4. PubMed PMID:\u00a0<\/span><span style=\"font-size: 13px; line-height: 19px;\">23460208; PubMed Central PMCID: PMC3627607.<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Stem cells Abad M, Mosteiro L, Pantoja C, Ca\u00f1amero M, Rayon T, Ors I, Gra\u00f1a O, Meg\u00edas D, Dom\u00ednguez O, Mart\u00ednez D, Manzanares M, Ortega S, Serrano M. Reprogramming in vivo\u00a0produces teratomas and iPS cells with totipotency features. Nature. 2013 Sep 11. doi: 10.1038\/nature12586. [Epub ahead of print] PubMed PMID: 24025773. Commentary: De Los Angeles [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[66],"tags":[271,298,314,86,262,453,97,313,57],"class_list":["post-1499","post","type-post","status-publish","format-standard","hentry","category-journal-club","tag-crispr","tag-crispr-cas","tag-flu-vaccine","tag-genetics","tag-genome-editing","tag-ig-nobel-prize","tag-medicine-2","tag-placenta","tag-stem-cells"],"_links":{"self":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/1499","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/comments?post=1499"}],"version-history":[{"count":2,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/1499\/revisions"}],"predecessor-version":[{"id":1501,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/1499\/revisions\/1501"}],"wp:attachment":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/media?parent=1499"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/categories?post=1499"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/tags?post=1499"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}