{"id":1492,"date":"2013-09-03T17:17:18","date_gmt":"2013-09-03T21:17:18","guid":{"rendered":"http:\/\/www.bio.purdue.edu\/lab\/leung\/blog\/?p=1492"},"modified":"2013-09-03T17:17:18","modified_gmt":"2013-09-03T21:17:18","slug":"2013-09-03-new-articles-we-read-this-week","status":"publish","type":"post","link":"https:\/\/leung.bio.purdue.edu\/blog\/2013-09-03-new-articles-we-read-this-week\/","title":{"rendered":"2013-09-03 new articles we read this week."},"content":{"rendered":"

Genetics<\/strong><\/p>\n

    \n
  1. Xiao A, Wang Z, Hu Y, Wu Y, Luo Z, Yang Z, Zu Y, Li W, Huang P, Tong X, Zhu Z,\u00a0Lin S, Zhang B. Chromosomal deletions and inversions mediated by TALENs and\u00a0CRISPR\/Cas in zebrafish. Nucleic Acids Res. 2013 Aug 1;41(14):e141.<\/span>doi:\u00a010.1093\/nar\/gkt464. Epub 2013 Jun 6. PubMed PMID: 23748566; PubMed Central PMCID:\u00a0PMC3737551.<\/span><\/li>\n
  2. Wei C, Liu J, Yu Z, Zhang B, Gao G, Jiao R. TALEN or Cas9 – rapid, efficient\u00a0<\/span>and specific choices for genome modifications. J Genet Genomics. 2013 Jun\u00a0<\/span>20;40(6):281-9. doi: 10.1016\/j.jgg.2013.03.013. Epub 2013 Apr 12. PubMed PMID:\u00a0<\/span>23790627.\u00a0<\/span><\/li>\n
  3. Gaj T, Gersbach CA, Barbas CF 3rd. ZFN, TALEN, and CRISPR\/Cas-based methods\u00a0<\/span>for genome engineering. Trends Biotechnol. 2013 Jul;31(7):397-405. doi:\u00a0<\/span>10.1016\/j.tibtech.2013.04.004. Epub 2013 May 9. PubMed PMID: 23664777; PubMed\u00a0<\/span>Central PMCID: PMC3694601.<\/span><\/li>\n
  4. Ochiai H, Fujita K, Suzuki K, Nishikawa M, Shibata T, Sakamoto N, Yamamoto T. Targeted mutagenesis in the sea urchin embryo using zinc-finger nucleases. Genes Cells. 2010 Aug;15(8):875-85. doi: 10.1111\/j.1365-2443.2010.01425.x. Epub 2010\u00a0Jul 2. PubMed PMID: 20604805.<\/span>\n
      \n
    • SSA assay<\/span><\/li>\n<\/ul>\n<\/li>\n
    • Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. High-throughput\u00a0profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease\u00a0specificity. Nat Biotechnol. 2013 Aug 11. doi: 10.1038\/nbt.2673. [Epub ahead of\u00a0print] PubMed PMID: 23934178.<\/span><\/li>\n
    • Bruder CE, Piotrowski A, Gijsbers AA, Andersson R, Erickson S, Diaz de St\u00e5hl\u00a0T, Menzel U, Sandgren J, von Tell D, Poplawski A, Crowley M, Crasto C, Partridge EC, Tiwari H, Allison DB, Komorowski J, van Ommen GJ, Boomsma DI, Pedersen NL,\u00a0den Dunnen JT, Wirdefeldt K, Dumanski JP. Phenotypically concordant and\u00a0discordant monozygotic twins display different DNA copy-number-variation\u00a0profiles. Am J Hum Genet. 2008 Mar;82(3):763-71. doi: 10.1016\/j.ajhg.2007.12.011.\u00a0Epub 2008 Feb 14. PubMed PMID: 18304490; PubMed Central PMCID: PMC2427204.<\/span><\/li>\n
    • Narlikar GJ, Sundaramoorthy R, Owen-Hughes T. Mechanisms and Functions of\u00a0<\/span>ATP-Dependent Chromatin-Remodeling Enzymes. Cell. 2013 Aug 1;154(3):490-503. doi:\u00a0<\/span>10.1016\/j.cell.2013.07.011. PubMed PMID: 23911317.<\/span><\/li>\n<\/ol>\n

      Cell cycle<\/strong><\/p>\n

        \n
      1. Jonas K, Liu J, Chien P, Laub MT. Proteotoxic Stress Induces a Cell-Cycle\u00a0Arrest by Stimulating Lon to Degrade the Replication Initiator DnaA. Cell. 2013\u00a0Aug 1;154(3):623-36. doi: 10.1016\/j.cell.2013.06.034. PubMed PMID: 23911325;\u00a0PubMed Central PMCID: PMC3749246.<\/span><\/li>\n<\/ol>\n

        \u00a0Disease gene mapping and sequencing<\/strong><\/p>\n

          \n
        1. Brunham LR, Hayden MR. Hunting human disease genes: lessons from the past,\u00a0challenges for the future. Hum Genet. 2013 Jun;132(6):603-17. doi:\u00a010.1007\/s00439-013-1286-3. Epub 2013 Mar 17. Review. PubMed PMID: 23504071;\u00a0PubMed Central PMCID: PMC3654184.<\/span><\/li>\n
        2. Shendure J, Lieberman Aiden E. The expanding scope of DNA sequencing. Nat\u00a0Biotechnol. 2012 Nov;30(11):1084-94. doi: 10.1038\/nbt.2421. Epub 2012 Nov 8.\u00a0Review. PubMed PMID: 23138308.<\/span><\/li>\n
        3. Gilissen C, Hoischen A, Brunner HG, Veltman JA. Disease gene identification\u00a0strategies for exome sequencing. Eur J Hum Genet. 2012 May;20(5):490-7. doi:\u00a010.1038\/ejhg.2011.258. Epub 2012 Jan 18. Review. PubMed PMID: 22258526; PubMed\u00a0Central PMCID: PMC3330229.<\/span><\/li>\n
        4. Ku CS, Cooper DN, Polychronakos C, Naidoo N, Wu M, Soong R. Exome sequencing:\u00a0<\/span>dual role as a discovery and diagnostic tool. Ann Neurol. 2012 Jan;71(1):5-14.\u00a0<\/span>doi: 10.1002\/ana.22647. Review. PubMed PMID: 22275248.<\/span><\/li>\n
        5. Goldstein DB, Allen A, Keebler J, Margulies EH, Petrou S, Petrovski S, Sunyaev\u00a0S. Sequencing studies in human genetics: design and interpretation. Nat Rev\u00a0Genet. 2013 Jul;14(7):460-70. doi: 10.1038\/nrg3455. Epub 2013 Jun 11. PubMed\u00a0PMID: 23752795.<\/span><\/li>\n
        6. Cirulli ET, Goldstein DB. Uncovering the roles of rare variants in common\u00a0disease through whole-genome sequencing. Nat Rev Genet. 2010 Jun;11(6):415-25.\u00a0doi: 10.1038\/nrg2779. Review. PubMed PMID: 20479773.<\/span><\/li>\n
        7. Rehm HL. Disease-targeted sequencing: a cornerstone in the clinic. Nat Rev\u00a0Genet. 2013 Apr;14(4):295-300. doi: 10.1038\/nrg3463. Epub 2013 Mar 12. PubMed\u00a0PMID: 23478348.<\/span><\/li>\n
        8. Gulsuner S, Walsh T, Watts AC, Lee MK, Thornton AM, Casadei S, Rippey C,\u00a0Shahin H; Consortium on the Genetics of Schizophrenia (COGS); PAARTNERS Study\u00a0Group, Nimgaonkar VL, Go RC, Savage RM, Swerdlow NR, Gur RE, Braff DL, King MC,\u00a0McClellan JM. Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell. 2013 Aug 1;154(3):518-29. doi:\u00a010.1016\/j.cell.2013.06.049. PubMed PMID: 23911319.<\/span><\/li>\n<\/ol>\n

          Alzheimer’s Disease<\/strong><\/p>\n

            \n
          1. Mullard A. Sting of Alzheimer’s failures offset by upcoming prevention trials.\u00a0Nat Rev Drug Discov. 2012 Sep;11(9):657-60. doi: 10.1038\/nrd3842. PubMed PMID:\u00a022935790.<\/span><\/li>\n
          2. Aisen PS, Vellas B, Hampel H. Moving towards early clinical trials for\u00a0amyloid-targeted therapy in Alzheimer’s disease. Nat Rev Drug Discov. 2013\u00a0Apr;12(4):324. doi: 10.1038\/nrd3842-c1. Epub 2013 Mar 15. PubMed PMID: 23493086.<\/span><\/li>\n
          3. Doody RS, Raman R, Farlow M, Iwatsubo T, Vellas B, Joffe S, Kieburtz K, He F, Sun X, Thomas RG, Aisen PS; Alzheimer’s Disease Cooperative Study SteeringCommittee, Siemers E, Sethuraman G, Mohs R; Semagacestat Study Group. A phase 3\u00a0trial of semagacestat for treatment of Alzheimer’s disease. N Engl J Med. 2013\u00a0Jul 25;369(4):341-50. doi: 10.1056\/NEJMoa1210951. PubMed PMID: 23883379.<\/span><\/li>\n
          4. Mullard A. Sting of Alzheimer’s failures offset by upcoming prevention trials.\u00a0Nat Rev Drug Discov. 2012 Sep;11(9):657-60. doi: 10.1038\/nrd3842. PubMed PMID:\u00a022935790.<\/span><\/li>\n
          5. Jonsson T, Atwal JK, Steinberg S, Snaedal J, Jonsson PV, Bjornsson S,\u00a0Stefansson H, Sulem P, Gudbjartsson D, Maloney J, Hoyte K, Gustafson A, Liu Y, Lu\u00a0Y, Bhangale T, Graham RR, Huttenlocher J, Bjornsdottir G, Andreassen OA, J\u00f6nsson EG, Palotie A, Behrens TW, Magnusson OT, Kong A, Thorsteinsdottir U, Watts RJ,\u00a0Stefansson K. A mutation in APP protects against Alzheimer’s disease and\u00a0<\/span>age-related cognitive decline. Nature. 2012 Aug 2;488(7409):96-9. doi:\u00a010.1038\/nature11283. PubMed PMID: 22801501.<\/span><\/li>\n<\/ol>\n

            Retinal development<\/strong><\/p>\n

              \n
            1. Suzuki SC, Bleckert A, Williams PR, Takechi M, Kawamura S, Wong RO. Cone\u00a0<\/span>photoreceptor types in zebrafish are generated by symmetric terminal divisions of\u00a0<\/span>dedicated precursors. Proc Natl Acad Sci U S A. 2013 Aug 26. [Epub ahead of\u00a0<\/span>print] PubMed PMID: 23980162.<\/span><\/li>\n<\/ol>\n

              Zebrafish<\/strong><\/p>\n

                \n
              1. Vignet C, B\u00e9gout ML, P\u00e9an S, Lyphout L, Leguay D, Cousin X. Systematic\u00a0<\/span>Screening of Behavioral Responses in Two Zebrafish Strains. Zebrafish. 2013 Jun\u00a0<\/span>5. [Epub ahead of print] PubMed PMID: 23738739.<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

                Genetics Xiao A, Wang Z, Hu Y, Wu Y, Luo Z, Yang Z, Zu Y, Li W, Huang P, Tong X, Zhu Z,\u00a0Lin S, Zhang B. Chromosomal deletions and inversions mediated by TALENs and\u00a0CRISPR\/Cas in zebrafish. Nucleic Acids Res. 2013 Aug 1;41(14):e141.doi:\u00a010.1093\/nar\/gkt464. Epub 2013 Jun 6. PubMed PMID: 23748566; PubMed Central PMCID:\u00a0PMC3737551. Wei C, Liu […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[75],"tags":[312,271,298,310,139,311,309,264,53],"class_list":["post-1492","post","type-post","status-publish","format-standard","hentry","category-journal-watch","tag-alzheimers-disease","tag-crispr","tag-crispr-cas","tag-disease-gene-mapping","tag-retinal-development","tag-sequencing","tag-ssa","tag-talen","tag-zebrafish"],"_links":{"self":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/1492","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/comments?post=1492"}],"version-history":[{"count":4,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/1492\/revisions"}],"predecessor-version":[{"id":1496,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/posts\/1492\/revisions\/1496"}],"wp:attachment":[{"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/media?parent=1492"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/categories?post=1492"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/leung.bio.purdue.edu\/blog\/wp-json\/wp\/v2\/tags?post=1492"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}